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Note 11 - Stockholders' Equity (Deficit) (Tables)
12 Months Ended
Dec. 31, 2018
Notes Tables  
Schedule of Stockholders' Equity Note, Warrants or Rights [Table Text Block]
 
       
Weighted-
 
   
 
 
 
 
Average
 
   
 
 
 
 
Exercise
 
(in thousands)
 
Warrants  
 
 
Price
 
Outstanding at December 31, 2015
   
1,458
    $
5.19
 
                 
Warrants granted
   
3,087
    $
1.91
 
                 
Warrants exercised
   
(3,977
)   $
1.95
 
                 
Warrants expired
   
(3
)   $
78.13
 
                 
Outstanding at December 31, 2016
   
565
    $
1.81
 
                 
Warrants granted
   
-
    $
-
 
                 
Warrants exercised
   
(21
)   $
1.81
 
                 
Warrants expired
   
-
    $
-
 
                 
Outstanding at December 31, 2017
   
544
    $
1.81
 
                 
Warrants granted
   
-
    $
-
 
                 
Warrants exercised
   
-
    $
-
 
                 
Warrants expired
   
-
    $
-
 
                 
Outstanding at December 31, 2018
   
544
    $
1.81