Note 11 - Stockholders' Equity (Deficit) (Details Textual)									3 Months Ended
	Feb. 05, 2018 USD ($) $ / shares shares	Sep. 29, 2016 USD ($) $ / shares	Aug. 01, 2016 USD ($) shares	May 05, 2016 USD ($) shares	Apr. 04, 2016 USD ($) $ / shares shares	Feb. 16, 2016 USD ($) $ / shares shares	Dec. 18, 2015	Dec. 11, 2015	Mar. 31, 2018 USD ($) $ / shares shares	Mar. 31, 2017 USD ($)	Dec. 31, 2016 USD ($) shares	Sep. 30, 2016 USD ($) shares	Dec. 31, 2017 $ / shares shares	Sep. 30, 2017 shares	Sep. 28, 2016 $ / shares	May 31, 2016 shares	Feb. 29, 2016 $ / shares	Jul. 31, 2011 $ / shares
Preferred Stock, Shares Authorized									5,000,000				5,000,000	5,000,000
Preferred Stock, Shares Outstanding, Ending Balance									0				0
Stock Issued During Period, Shares, New Issues						1,518,567
Stock Issued During Period, Value, New Issues | $						$ 2,800,000
Class of Warrant or Right, Exercise Price, Discount from Market Price		16.00%
Private Placement, Commission Percentage					6.00%	6.00%					6.00%	6.00%
Common Stock, Par or Stated Value Per Share | $ / shares									$ 0.01				$ 0.01
Class of Warrant or Right, Number of Securities Called by Warrants or Rights											363,523	3,613,284				2,039,530
Class of Warrant or Right, Exercise Price of Warrants or Rights | $ / shares		$ 3.15							$ 1.81				$ 1.81		$ 19.50			$ 33.25
Proceeds from Warrant Exercises | $											$ 900,000	$ 6,600,000
Class of Warrant or Right, Exercised During Period											363,523	3,613,284
Warrants Exercised, Commission Paid | $											$ 32,000	$ 338,000
Fair Value Adjustment of Warrants | $									$ (214,000)	$ 235,000
General and Administrative Expense [Member]
Fair Value Adjustment of Warrants | $		$ 270,000
July 2011, March 2015, and October 2015 Warrants [Member]
Class of Warrant or Right, Number of Securities Called by Warrants or Rights											363,523	3,613,284
Proceeds from Warrant Exercises | $											$ 900,000	$ 6,900,000
Class of Warrant or Right, Exercised During Period											363,523	3,613,284
Mr. Fu [Member]
Stock Issued During Period, Shares, New Issues						696,590
Shares Issued, Price Per Share | $ / shares						$ 1.81
Class of Warrant or Right, Exercise Price, Discount from Market Price						5.00%
Mr. Fu [Member] | July 2011, March 2015, and October 2015 Warrants [Member]
Shares Issued, Price Per Share | $ / shares																	$ 1.81
Class of Warrant or Right, Exercise Price of Warrants or Rights | $ / shares																	$ 1.81
Pioneer Pharma Co. [Member]
Stock Issued During Period, Shares, New Issues						696,590
Shares Issued, Price Per Share | $ / shares						$ 1.91
Mr. Sieczkarek [Member]
Stock Issued During Period, Shares, New Issues						125,387
Shares Issued, Price Per Share | $ / shares						$ 1.91
Private Placement [Member]
Stock Issued During Period, Shares, New Issues			2,094,241	4,079,058	6,173,299
Common Stock, Par or Stated Value Per Share | $ / shares					$ 0.01
Class of Warrant or Right, Number of Securities Called by Warrants or Rights			1,047,121	2,039,530	3,086,651
Sale of Stock, Consideration Received on Transaction | $			$ 4,000,000	$ 7,800,000	$ 11,800,000
Warrant Expiration Term					4 years
Class of Warrant or Right, Exercise Price of Warrants or Rights | $ / shares					$ 1.91
Number of Sequential Trading Days					5 days
Private Placement [Member] | Minimum [Member]
Common Stock, Closing Price | $ / shares					$ 4
Private Placement [Member] | China Kington Asset Management Co. Ltd. [Member]
Private Placement, Commission Percentage									6.00%
Payments of Stock Issuance Costs | $					$ 618,000	$ 155,000			$ 359,040
Warrants Exercised, Commission Paid | $									$ 34,000
Private Placement [Member] | OP Financial Investments Limited [Member]
Stock Issued During Period, Shares, New Issues	1,700,000
Stock Issued During Period, Value, New Issues | $	$ 5,984,000
Common Stock, Par or Stated Value Per Share | $ / shares	$ 0.01
Reverse Stock Split [Member]
Stockholders' Equity Note, Stock Split, Conversion Ratio							25	25