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Note 11 - Stockholders' Equity (Deficit) - Outstanding Warrants (Details) - $ / shares
3 Months Ended 12 Months Ended
Dec. 31, 2016
Sep. 30, 2016
Dec. 31, 2017
Dec. 31, 2016
Dec. 31, 2015
Warrants outstanding (in shares)     565,000 1,458,000 197,000
Warrants outstanding, weighted average exercise price (in dollars per share)     $ 1.81 $ 5.19 $ 35.23
Warrants granted (in shares)     3,087,000 1,317,000
Warrants granted, weighted average exercise price (in dollars per share)     $ 1.91 $ 7.40
Warrants expired (in shares)     (3,000) (56,000)
Warrants expired, weighted average exercise price (in dollars per share)     $ 78.13 $ 39
Warrants exercised (in shares) (363,523) (3,613,284) (21,000) (3,977,000)  
Warrants exercised, weighted average exercise price (in dollars per share)     $ 1.81 $ 1.95  
Warrants outstanding (in shares) 565,000   544,000 565,000 1,458,000
Warrants outstanding, weighted average exercise price (in dollars per share) $ 1.81   $ 1.81 $ 1.81 $ 5.19