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Note 5 - Property and Equipment (Tables)
3 Months Ended
Mar. 31, 2016
Notes Tables  
Property, Plant and Equipment [Table Text Block]
(in thousands)
 
March 31, 2016
 
 
December 31, 2015
 
Office and laboratory equipment
  $ 1,639     $ 1,633  
Furniture and fixtures
    257       254  
Software
    37       37  
Leasehold improvements
    179       173  
Total property and equipment, at cost
    2,112       2,097  
Less: accumulated depreciation
    (1,742 )     (1,702 )
Net property and equipment
  $ 370     $ 395