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Income Taxes - Additional Information (Details) - USD ($)
12 Months Ended
Dec. 31, 2018
Dec. 31, 2017
Dec. 31, 2016
Income Tax Disclosure [Line Items]      
U.S. statutory tax rate 21.00%    
Provision for income taxes $ 44,000 $ 0 $ 0
Benefit recognized for net operating loss carryforwards 0    
Benefit recognized for other deferred tax assets 0    
Increase (decrease) in valuation allowance 21,700,000 (600,000)  
Net operating loss carryforwards, federal 206,700,000    
Net operating loss carryforwards, state 107,400,000    
Tax credit carryforward 3,700,000    
Tax credit carryforwards available to reduce future taxable income $ 2,400,000    
Tax credit carryforwards expiration beginning year 2028    
Unrecognized tax benefit $ 1,500,000 900,000 $ 600,000
Accrual for interest or penalties related to unrecognized tax benefits $ 0 $ 0  
Federal      
Income Tax Disclosure [Line Items]      
Net operating loss carry forwards expiration year 2027    
State      
Income Tax Disclosure [Line Items]      
Net operating loss carry forwards expiration year 2019