The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
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COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
4D MOLECULAR THERAPEUTICS IN COM 35104E100   44,604,000 1,400,000 SH   SOLE   1,400,000 0 0
ABCELLERA BIOLOGICS INC COM 00288U106   5,104,925 1,126,915 SH   SOLE   1,126,915 0 0
ALIBABA GROUP HLDG LTD SPONSORED ADS 01609W102   36,239,842 500,827 SH   SOLE   500,827 0 0
ALNYLAM PHARMACEUTICALS INC COM 02043Q107   17,692,339 118,383 SH   SOLE   118,383 0 0
AMICUS THERAPEUTICS INC COM 03152W109   29,450,000 2,500,000 SH   SOLE   2,500,000 0 0
APPLE INC COM 037833100   31,373,981 182,960 SH   SOLE   182,960 0 0
ARRIVENT BIOPHARMA INC COM 04272N102   19,237,720 1,077,140 SH   SOLE   1,077,140 0 0
ASML HOLDING N V N Y REGISTRY SHS N07059210   177,145,712 182,536 SH   SOLE   182,536 0 0
BIOMARIN PHARMACEUTICAL INC COM 09061G101   39,303,000 450,000 SH   SOLE   450,000 0 0
BLUEPRINT MEDICINES CORP COM 09627Y109   34,019,262 358,626 SH   SOLE   358,626 0 0
BROOKFIELD ASSET MANAGMT LTD CL A LMT VTG SHS 113004105   26,355,238 627,207 SH   SOLE   627,207 0 0
BROOKFIELD CORP CL A LTD VT SH 11271J107   162,465,230 3,880,230 SH   SOLE   3,880,230 0 0
CABLE ONE INC COM 12685J105   50,099,861 118,403 SH   SOLE   118,403 0 0
CARGO THERAPEUTICS INC COM 14179K101   27,900,000 1,250,000 SH   SOLE   1,250,000 0 0
CORCEPT THERAPEUTICS INC COM 218352102   60,742,209 2,411,362 SH   SOLE   2,411,362 0 0
CRINETICS PHARMACEUTICALS IN COM 22663K107   51,425,466 1,098,600 SH   SOLE   1,098,600 0 0
EDGEWISE THERAPEUTICS INC COM 28035Q102   115,722,403 6,344,430 SH   SOLE   6,344,430 0 0
GALECTO INC COM 36322Q107   1,948,277 2,497,791 SH   SOLE   2,497,791 0 0
INSMED INC COM PAR $.01 457669307   36,335,318 1,339,304 SH   SOLE   1,339,304 0 0
INSPIRE MED SYS INC COM 457730109   14,073,900 65,524 SH   SOLE   65,524 0 0
IO BIOTECH INC COM 449778109   8,802,686 5,088,258 SH   SOLE   5,088,258 0 0
KYVERNA THERAPEUTICS INC COM 501976104   17,388,000 700,000 SH   SOLE   700,000 0 0
LANZATECH GLOBAL INC COM 51655R101   48,946,945 15,814,845 SH   SOLE   15,814,845 0 0
LEXEO THERAPEUTICS INC COM 52886X107   25,688,513 1,638,298 SH   SOLE   1,638,298 0 0
MARQETA INC CLASS A COM 57142B104   2,631,686 441,558 SH   SOLE   441,558 0 0
METAGENOMI INC COM 59102M104   18,348,296 1,739,175 SH   SOLE   1,739,175 0 0
MIRUM PHARMACEUTICALS INC COM 604749101   37,680,000 1,500,000 SH   SOLE   1,500,000 0 0
PHARVARIS N V COM N69605108   26,993,173 1,168,030 SH   SOLE   1,168,030 0 0
ROCKET PHARMACEUTICALS INC COM 77313F106   28,287,000 1,050,000 SH   SOLE   1,050,000 0 0
SALESFORCE INC COM 79466L302   144,614,589 480,160 SH   SOLE   480,160 0 0
SPERO THERAPEUTICS INC COM 84833T103   806,511 468,902 SH   SOLE   468,902 0 0
TREACE MED CONCEPTS INC COM 89455T109   4,698,000 360,000 SH   SOLE   360,000 0 0
VAXCYTE INC COM 92243G108   57,721,950 845,000 SH   SOLE   845,000 0 0
VIRIDIAN THERAPEUTICS INC COM 92790C104   19,261,000 1,100,000 SH   SOLE   1,100,000 0 0
VERVE THERAPEUTICS INC COM 92539P101   26,560,000 2,000,000 SH   SOLE   2,000,000 0 0