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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
Originator-Key-Asymmetric:
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 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 K29FwxA+1rsyhGgHkpvz1rI66KRKTlisP6hGD24lJ/YQt+2/hBhEl1QJzBSoMEf7
 2Yzl3UboxbZvX5LN5CBRQA==

<SEC-DOCUMENT>0001383701-10-000003.txt : 20101028
<SEC-HEADER>0001383701-10-000003.hdr.sgml : 20101028
<ACCEPTANCE-DATETIME>20101028172351
ACCESSION NUMBER:		0001383701-10-000003
CONFORMED SUBMISSION TYPE:	D
PUBLIC DOCUMENT COUNT:		1
ITEM INFORMATION:		Rule 506
FILED AS OF DATE:		20101028
DATE AS OF CHANGE:		20101028
EFFECTIVENESS DATE:		20101028

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Conatus Pharmaceuticals Inc
		CENTRAL INDEX KEY:			0001383701
		IRS NUMBER:				203183915
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		D
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	021-149755
		FILM NUMBER:		101149084

	BUSINESS ADDRESS:	
		STREET 1:		4365 Executive Dirve
		STREET 2:		Suite 200
		CITY:			San Diego
		STATE:			CA
		ZIP:			92121
		BUSINESS PHONE:		(858) 457-7221

	MAIL ADDRESS:	
		STREET 1:		4365 Executive Dirve
		STREET 2:		Suite 200
		CITY:			San Diego
		STATE:			CA
		ZIP:			92121
</SEC-HEADER>
<DOCUMENT>
<TYPE>D
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
<XML>
<?xml version="1.0"?>
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    <schemaVersion>X0704</schemaVersion>

    <submissionType>D</submissionType>

    <testOrLive>LIVE</testOrLive>

    <primaryIssuer>
        <cik>0001383701</cik>
        <entityName>Conatus Pharmaceuticals Inc</entityName>
        <issuerAddress>
            <street1>4365 Executive Drive</street1>
            <street2>Suite 200</street2>
            <city>San Diego</city>
            <stateOrCountry>CA</stateOrCountry>
            <stateOrCountryDescription>CALIFORNIA</stateOrCountryDescription>
            <zipCode>92121</zipCode>
        </issuerAddress>
        <issuerPhoneNumber>(858) 457-7221</issuerPhoneNumber>
        <jurisdictionOfInc>DELAWARE</jurisdictionOfInc>
        <issuerPreviousNameList>
            <value>None</value>
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        <edgarPreviousNameList>
            <value>None</value>
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        <entityType>Corporation</entityType>
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    <relatedPersonsList>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Steven</firstName>
                <middleName>J.</middleName>
                <lastName>Mento</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o Conatus Pharmaceuticals Inc.</street1>
                <street2>4365 Executive Drive, Suite 200</street2>
                <city>San Diego</city>
                <stateOrCountry>CA</stateOrCountry>
                <stateOrCountryDescription>CALIFORNIA</stateOrCountryDescription>
                <zipCode>92121</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>William</firstName>
                <lastName>Gerber</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o Conatus Pharmaceuticals Inc.</street1>
                <street2>4365 Executive Drive, Suite 200</street2>
                <city>San Diego</city>
                <stateOrCountry>CA</stateOrCountry>
                <stateOrCountryDescription>CALIFORNIA</stateOrCountryDescription>
                <zipCode>92121</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
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            <relationshipClarification></relationshipClarification>
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        <relatedPersonInfo>
            <relatedPersonName>
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                <middleName>F.</middleName>
                <lastName>Hale</lastName>
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            <relatedPersonAddress>
                <street1>c/o Conatus Pharmaceuticals Inc.</street1>
                <street2>4365 Executive Drive, Suite 200</street2>
                <city>San Diego</city>
                <stateOrCountry>CA</stateOrCountry>
                <stateOrCountryDescription>CALIFORNIA</stateOrCountryDescription>
                <zipCode>92121</zipCode>
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            <relatedPersonRelationshipList>
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            <relationshipClarification></relationshipClarification>
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        <relatedPersonInfo>
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                <firstName>Paul</firstName>
                <lastName>Klingenstein</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o Conatus Pharmaceuticals Inc.</street1>
                <street2>4365 Executive Drive, Suite 200</street2>
                <city>San Diego</city>
                <stateOrCountry>CA</stateOrCountry>
                <stateOrCountryDescription>CALIFORNIA</stateOrCountryDescription>
                <zipCode>92121</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
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            <relationshipClarification></relationshipClarification>
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        <relatedPersonInfo>
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                <firstName>Shahzad</firstName>
                <lastName>Malik</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o Conatus Pharmaceuticals Inc.</street1>
                <street2>4365 Executive Drive, Suite 200</street2>
                <city>San Diego</city>
                <stateOrCountry>CA</stateOrCountry>
                <stateOrCountryDescription>CALIFORNIA</stateOrCountryDescription>
                <zipCode>92121</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Marc</firstName>
                <lastName>Peret</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o Conatus Pharmaceuticals Inc.</street1>
                <street2>4365 Executive Drive, Suite 200</street2>
                <city>San Diego</city>
                <stateOrCountry>CA</stateOrCountry>
                <stateOrCountryDescription>CALIFORNIA</stateOrCountryDescription>
                <zipCode>92121</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Harold</firstName>
                <lastName>Van Wart</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o Conatus Pharmaceuticals Inc.</street1>
                <street2>4365 Executive Drive, Suite 200</street2>
                <city>San Diego</city>
                <stateOrCountry>CA</stateOrCountry>
                <stateOrCountryDescription>CALIFORNIA</stateOrCountryDescription>
                <zipCode>92121</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Alfred</firstName>
                <middleName>P.</middleName>
                <lastName>Spada</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o Conatus Pharmaceuticals Inc.</street1>
                <street2>4365 Executive Drive, Suite 200</street2>
                <city>San Diego</city>
                <stateOrCountry>CA</stateOrCountry>
                <stateOrCountryDescription>CALIFORNIA</stateOrCountryDescription>
                <zipCode>92121</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Charles</firstName>
                <middleName>J.</middleName>
                <lastName>Cashion</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o Conatus Pharmaceuticals Inc.</street1>
                <street2>4365 Executive Drive, Suite 200</street2>
                <city>San Diego</city>
                <stateOrCountry>CA</stateOrCountry>
                <stateOrCountryDescription>CALIFORNIA</stateOrCountryDescription>
                <zipCode>92121</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Jennifer</firstName>
                <middleName>Giottonini</middleName>
                <lastName>Cayer</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o Conatus Pharmaceuticals Inc.</street1>
                <street2>4365 Executive Drive, Suite 200</street2>
                <city>San Diego</city>
                <stateOrCountry>CA</stateOrCountry>
                <stateOrCountryDescription>CALIFORNIA</stateOrCountryDescription>
                <zipCode>92121</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
    </relatedPersonsList>

    <offeringData>
        <industryGroup>
            <industryGroupType>Biotechnology</industryGroupType>
        </industryGroup>
        <issuerSize>
            <revenueRange>Decline to Disclose</revenueRange>
        </issuerSize>
        <federalExemptionsExclusions>
            <item>06</item>
        </federalExemptionsExclusions>
        <typeOfFiling>
            <newOrAmendment>
                <isAmendment>false</isAmendment>
            </newOrAmendment>
            <dateOfFirstSale>
                <value>2010-03-05</value>
            </dateOfFirstSale>
        </typeOfFiling>
        <durationOfOffering>
            <moreThanOneYear>false</moreThanOneYear>
        </durationOfOffering>
        <typesOfSecuritiesOffered>
            <isDebtType>true</isDebtType>
            <isOptionToAcquireType>true</isOptionToAcquireType>
        </typesOfSecuritiesOffered>
        <businessCombinationTransaction>
            <isBusinessCombinationTransaction>false</isBusinessCombinationTransaction>
            <clarificationOfResponse></clarificationOfResponse>
        </businessCombinationTransaction>
        <minimumInvestmentAccepted>0</minimumInvestmentAccepted>
        <salesCompensationList></salesCompensationList>
        <offeringSalesAmounts>
            <totalOfferingAmount>5000000</totalOfferingAmount>
            <totalAmountSold>5000000</totalAmountSold>
            <totalRemaining>0</totalRemaining>
            <clarificationOfResponse>Total Offering Amount and Total Amount Sold is the sum of the first closing and second closing which occurred on March 5, 2010 and October 15, 2010, respectively.</clarificationOfResponse>
        </offeringSalesAmounts>
        <investors>
            <hasNonAccreditedInvestors>false</hasNonAccreditedInvestors>
            <totalNumberAlreadyInvested>15</totalNumberAlreadyInvested>
        </investors>
        <salesCommissionsFindersFees>
            <salesCommissions>
                <dollarAmount>0</dollarAmount>
            </salesCommissions>
            <findersFees>
                <dollarAmount>0</dollarAmount>
            </findersFees>
            <clarificationOfResponse></clarificationOfResponse>
        </salesCommissionsFindersFees>
        <useOfProceeds>
            <grossProceedsUsed>
                <dollarAmount>0</dollarAmount>
            </grossProceedsUsed>
            <clarificationOfResponse></clarificationOfResponse>
        </useOfProceeds>
        <signatureBlock>
            <authorizedRepresentative>false</authorizedRepresentative>
            <signature>
                <issuerName>Conatus Pharmaceuticals Inc</issuerName>
                <signatureName>/s/ Charles J. Cashion</signatureName>
                <nameOfSigner>Charles J. Cashion</nameOfSigner>
                <signatureTitle>SVP Finance, CFO and Secretary</signatureTitle>
                <signatureDate>2010-10-28</signatureDate>
            </signature>
        </signatureBlock>
    </offeringData>
</edgarSubmission>
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</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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