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Organization and Principal Activities - Additional Information (Details)
$ in Thousands
6 Months Ended
Jun. 30, 2024
USD ($)
Segment
Dec. 31, 2023
USD ($)
Organization Consolidation And Presentation Of Financial Statements [Line Items]    
Date of incorporation Apr. 21, 2003  
Headquartered in South San Francisco  
Headquartered in state CA  
Number of operating segments | Segment 1  
Accumulated deficit $ 665,639 $ 559,408
Unrestricted cash, cash equivalents and marketable securities $ 375,600  
Substantial doubt about going concern, within one year false  
Vaxcyte    
Organization Consolidation And Presentation Of Financial Statements [Line Items]    
Unrestricted cash, cash equivalents and equity securities at carrying value $ 50,400  
Minimum    
Organization Consolidation And Presentation Of Financial Statements [Line Items]    
Period from issuance date of unaudited interim condensed financial statements 12 months