Net Loss per Share (Tables)

12 Months Ended

Dec. 31, 2021

Net Loss per Share

Schedule of computation of the basic and diluted net loss per share attributable to common stockholders

	Year Ended December 31,
	2021		2020		2019
Numerator:
Net loss	$	(125,551)	$	(66,150)	$	(77,187)
Denominator:
Weighted-average shares used to compute net loss per common share, basic and diluted		46,322,910		34,396,446		25,894,024
Net loss per share, basic and diluted	$	(2.71)	$	(1.92)	$	(2.98)

Schedule of potentially dilutive securities excluded from diluted net loss per share calculations

	December 31,
	2021	2020	2019
Options to purchase common stock	5,890,540	4,648,120	3,681,521
Common stock warrants	2,750,000	2,750,000	2,750,000
Restricted stock units	405,972	244,545	278,482
Performance stock units	105,500	—	—
ESPP shares	18,055	28,445	40,275
Total	9,170,067	7,671,110	6,750,278