Property and Equipment, Net - Summary of Property and Equipment (Details) - USD ($) $ in Thousands	Mar. 31, 2022	Dec. 31, 2021
Property, Plant and Equipment [Line Items]
Finance lease right-of-use asset	$ 189	$ 189
Property and equipment, gross	42,201	42,043
Less: accumulated depreciation	(33,442)	(32,878)
Property and equipment, net	8,759	9,165
Leasehold improvements
Property, Plant and Equipment [Line Items]
Property and equipment, gross	9,170	9,052
Laboratory and clean room equipment
Property, Plant and Equipment [Line Items]
Property and equipment, gross	16,255	16,567
Furniture and equipment
Property, Plant and Equipment [Line Items]
Property and equipment, gross	14,975	14,975
Construction in progress
Property, Plant and Equipment [Line Items]
Property and equipment, gross	683	397
Asset retirement cost
Property, Plant and Equipment [Line Items]
Property and equipment, gross	$ 929	$ 863