Property and Equipment - Summary of Property and Equipment (Details) - USD ($) $ in Thousands	Mar. 31, 2021	Dec. 31, 2020
Property, Plant and Equipment [Line Items]
Property and equipment, gross	$ 41,089	$ 40,935
Less accumulated depreciation	(30,045)	(29,498)
Property and equipment, net	11,044	11,437
Leasehold improvements
Property, Plant and Equipment [Line Items]
Property and equipment, gross	6,010	6,010
Laboratory and clean room equipment
Property, Plant and Equipment [Line Items]
Property and equipment, gross	14,828	15,524
Furniture and equipment
Property, Plant and Equipment [Line Items]
Property and equipment, gross	15,137	15,295
Construction in progress
Property, Plant and Equipment [Line Items]
Property and equipment, gross	4,295	3,321
Asset retirement cost
Property, Plant and Equipment [Line Items]
Property and equipment, gross	$ 819	$ 785

Amount of accumulated depreciation, depletion and amortization for physical assets used in the normal conduct of business to produce goods and services.

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Amount before accumulated depreciation, depletion and amortization of physical assets used in the normal conduct of business and not intended for resale. Examples include, but are not limited to, land, buildings, machinery and equipment, office equipment, and furniture and fixtures.

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