Intangible Assets and Royalty Agreement - Summary of Intangible Assets (Details) - USD ($)		9 Months Ended
	Jan. 29, 2007	Sep. 30, 2017	Dec. 31, 2016	Jan. 13, 2016	Jan. 05, 2011
Finite-Lived Intangible Assets [Line Items]
Total		$ 16,887,000	$ 30,260,000
Less Accumulated amortization and impairment charges		(6,510,000)	(6,992,000)
Net		10,377,000	23,268,000
Tradenames & trademarks
Finite-Lived Intangible Assets [Line Items]
Gross carrying value, indefinite lived		1,008,000	1,458,000
Tradenames & trademarks | Stability Biologics, LLC
Finite-Lived Intangible Assets [Line Items]
Gross carrying value, indefinite lived				$ 450,000
Tradenames & trademarks | Surgical Biologics, LLC
Finite-Lived Intangible Assets [Line Items]
Gross carrying value, indefinite lived					$ 1,008,000
In process research & development
Finite-Lived Intangible Assets [Line Items]
Gross carrying value, indefinite lived		25,000	25,000
In process research & development | Surgical Biologics, LLC
Finite-Lived Intangible Assets [Line Items]
Gross carrying value, indefinite lived					25,000
Patents in process
Finite-Lived Intangible Assets [Line Items]
Gross carrying value, indefinite lived		$ 1,742,000	2,618,000
Licenses
Finite-Lived Intangible Assets [Line Items]
Weighted average amortization lives		7 years
Gross carrying value		$ 1,009,000	1,399,000
Licenses | Stability Biologics, LLC
Finite-Lived Intangible Assets [Line Items]
Gross carrying value				390,000
Licenses | Shriners Hospitals for Children and University of South Florida Research Foundation, Inc.
Finite-Lived Intangible Assets [Line Items]
Acquisition price	$ 996,000
Maximum time of approval	30 days
Fair value of earn-out	$ 200,000
Contingent royalty to be paid to licensor	3.00%
Annual royalty payment, minimum	$ 50,000
Licenses | Surgical Biologics, LLC
Finite-Lived Intangible Assets [Line Items]
Gross carrying value					13,000
Patents and know-how
Finite-Lived Intangible Assets [Line Items]
Weighted average amortization lives		19 years
Gross carrying value		$ 8,712,000	14,839,000
Patents and know-how | Stability Biologics, LLC
Finite-Lived Intangible Assets [Line Items]
Gross carrying value				6,790,000
Patents and know-how | Surgical Biologics, LLC
Finite-Lived Intangible Assets [Line Items]
Gross carrying value					7,690,000
Finite lived intangible assets		$ 663,000
Customer & supplier relationships
Finite-Lived Intangible Assets [Line Items]
Weighted average amortization lives		13 years
Gross carrying value		$ 4,271,000	9,091,000
Customer & supplier relationships | Stability Biologics, LLC
Finite-Lived Intangible Assets [Line Items]
Gross carrying value				5,330,000
Customer & supplier relationships | Surgical Biologics, LLC
Finite-Lived Intangible Assets [Line Items]
Gross carrying value					$ 3,761,000
Non compete agreements
Finite-Lived Intangible Assets [Line Items]
Weighted average amortization lives		4 years
Gross carrying value		$ 120,000	$ 830,000
Non compete agreements | Stability Biologics, LLC
Finite-Lived Intangible Assets [Line Items]
Gross carrying value				$ 830,000