Intangible Assets and Royalty Agreement - Intangible Asssets Activity Summary (Details) - USD ($)		12 Months Ended
	Jan. 29, 2007	Dec. 31, 2016	Mar. 31, 2016	Jan. 13, 2016	Dec. 31, 2015	Jan. 05, 2011
Finite-Lived Intangible Assets [Line Items]
Intangible assets, gross carrying value		$ 30,260,000			$ 15,627,000
Less Accumulated amortization and impairment charges		(6,992,000)			(4,864,000)
Intangible Assets, Net		23,268,000			10,763,000
Net book value of intangible assets		21,810,000
Stability Biologics, LLC
Finite-Lived Intangible Assets [Line Items]
Fair value of earn-out		17,450,000	$ 25,620,000	$ 17,450,000
Tradenames & Trademarks
Finite-Lived Intangible Assets [Line Items]
Gross carrying value, indefinite lived		1,458,000			1,008,000
Tradenames & Trademarks | Stability Biologics, LLC
Finite-Lived Intangible Assets [Line Items]
Gross carrying value, indefinite lived				450,000
Tradenames & Trademarks | Surgical Biologics, LLC
Finite-Lived Intangible Assets [Line Items]
Gross carrying value, indefinite lived						$ 1,008,000
In Process Research & Development
Finite-Lived Intangible Assets [Line Items]
Gross carrying value, indefinite lived		25,000			25,000
In Process Research & Development | Surgical Biologics, LLC
Finite-Lived Intangible Assets [Line Items]
Gross carrying value, indefinite lived						25,000
Patents in Process
Finite-Lived Intangible Assets [Line Items]
Gross carrying value, indefinite lived		$ 2,618,000			1,823,000
Licenses
Finite-Lived Intangible Assets [Line Items]
Weighted Average Amortization Lives		7 years
Gross carrying value		$ 1,399,000			1,009,000
Licenses | Stability Biologics, LLC
Finite-Lived Intangible Assets [Line Items]
Gross carrying value				390,000
Licenses | Shriners Hospitals for Children and University of South Florida Research Foundation, Inc.
Finite-Lived Intangible Assets [Line Items]
Acquisition price	$ 996,000
Maximum time of approval	30 days
Fair value of earn-out	$ 200,000
Contingent royalty to be paid to licensor	3.00%
Annual royalty payment	$ 50,000
Net book value of intangible assets		$ 10,000
Licenses | Surgical Biologics, LLC
Finite-Lived Intangible Assets [Line Items]
Gross carrying value						13,000
Patents and know-how
Finite-Lived Intangible Assets [Line Items]
Weighted Average Amortization Lives		19 years
Gross carrying value		$ 14,839,000			8,001,000
Patents and know-how | Stability Biologics, LLC
Finite-Lived Intangible Assets [Line Items]
Gross carrying value				6,790,000
Patents and know-how | Surgical Biologics, LLC
Finite-Lived Intangible Assets [Line Items]
Gross carrying value						7,690,000
Finite-lived intangible assets, costs		$ 48,000
Customer & Supplier Relationships
Finite-Lived Intangible Assets [Line Items]
Weighted Average Amortization Lives		13 years
Gross carrying value		$ 9,091,000			3,761,000
Customer & Supplier Relationships | Stability Biologics, LLC
Finite-Lived Intangible Assets [Line Items]
Gross carrying value				5,330,000
Customer & Supplier Relationships | Surgical Biologics, LLC
Finite-Lived Intangible Assets [Line Items]
Gross carrying value						$ 3,761,000
Non-Compete Agreements
Finite-Lived Intangible Assets [Line Items]
Weighted Average Amortization Lives		4 years
Gross carrying value		$ 830,000			$ 0
Non-Compete Agreements | Stability Biologics, LLC
Finite-Lived Intangible Assets [Line Items]
Gross carrying value				$ 830,000