Intangible Assets and Royalty Agreement - Summary of Intangible Assets (Details) - USD ($)		9 Months Ended
	Jan. 29, 2007	Sep. 30, 2016	Jan. 13, 2016	Dec. 31, 2015	Jan. 05, 2011
Finite-Lived Intangible Assets [Line Items]
Total		$ 34,002,000		$ 15,627,000
Less Accumulated amortization and impairment charges		(6,753,000)		(4,864,000)
Net		27,249,000		10,763,000
Stability Biologics, LLC
Finite-Lived Intangible Assets [Line Items]
Fair value of earn-out		$ 25,620,000	$ 25,620,000
Licenses
Finite-Lived Intangible Assets [Line Items]
Weighted average amortization lives		7 years
Gross carrying value		$ 1,699,000		1,009,000
Licenses | Stability Biologics, LLC
Finite-Lived Intangible Assets [Line Items]
Gross carrying value			690,000
Licenses | Shriners Hospitals for Children and University of South Florida Research Foundation, Inc.
Finite-Lived Intangible Assets [Line Items]
Acquisition price	$ 996,000
Maximum time of approval	30 days
Fair value of earn-out	$ 200,000
Contingent royalty to be paid to licensor	3.00%
Annual royalty payment, minimum	$ 50,000
Licenses | Surgical Biologics, LLC
Finite-Lived Intangible Assets [Line Items]
Gross carrying value					$ 13,000
Patents and know-how
Finite-Lived Intangible Assets [Line Items]
Weighted average amortization lives		19 years
Gross carrying value		$ 17,211,000		8,001,000
Patents and know-how | Stability Biologics, LLC
Finite-Lived Intangible Assets [Line Items]
Gross carrying value			9,170,000
Patents and know-how | Surgical Biologics, LLC
Finite-Lived Intangible Assets [Line Items]
Gross carrying value					7,690,000
Finite lived intangible assets		$ 40,000
Customer & supplier relationships
Finite-Lived Intangible Assets [Line Items]
Weighted average amortization lives		13 years
Gross carrying value		$ 9,851,000		3,761,000
Customer & supplier relationships | Stability Biologics, LLC
Finite-Lived Intangible Assets [Line Items]
Gross carrying value			6,090,000
Customer & supplier relationships | Surgical Biologics, LLC
Finite-Lived Intangible Assets [Line Items]
Gross carrying value					3,761,000
Non compete agreements
Finite-Lived Intangible Assets [Line Items]
Weighted average amortization lives		4 years
Gross carrying value		$ 1,080,000		0
Non compete agreements | Stability Biologics, LLC
Finite-Lived Intangible Assets [Line Items]
Gross carrying value			1,080,000
Tradenames & trademarks
Finite-Lived Intangible Assets [Line Items]
Gross carrying value, indefinite lived		1,838,000		1,008,000
Tradenames & trademarks | Stability Biologics, LLC
Finite-Lived Intangible Assets [Line Items]
Gross carrying value, indefinite lived			$ 830,000
Tradenames & trademarks | Surgical Biologics, LLC
Finite-Lived Intangible Assets [Line Items]
Gross carrying value, indefinite lived					1,008,000
In process research & development
Finite-Lived Intangible Assets [Line Items]
Gross carrying value, indefinite lived		25,000		25,000
In process research & development | Surgical Biologics, LLC
Finite-Lived Intangible Assets [Line Items]
Gross carrying value, indefinite lived					$ 25,000
Patents in process
Finite-Lived Intangible Assets [Line Items]
Gross carrying value, indefinite lived		$ 2,298,000		$ 1,823,000