Consolidated Statements of Operations and Comprehensive Loss (USD $) In Thousands, except Per Share data, unless otherwise specified	3 Months Ended
	Mar. 31, 2014	Mar. 31, 2013
Revenue:
Net product revenue	$ 6,770	$ 6,893
Contract revenue	904	88
Total revenue	7,674	6,981
Operating expenses:
Cost of sales	3,382	4,158
Royalty expense	363	282
Research and development	3,538	3,236
Selling, general and administrative	27,651	14,482
Total operating expenses	34,934	22,158
Loss from operations	(27,260)	(15,177)
Other income (expense):
Interest income	6	8
Interest expense	(1,886)	(1,613)
Fair Value, Option, Changes in Fair Value, Gain (Loss)	8,269	(4,258)
Change in fair value of embedded derivatives	(14)	(81)
Other income (expense)	(47)	66
Total other income (expense)	6,328	(5,878)
Net loss before income taxes	(20,932)	(21,055)
Provision for income taxes	0	0
Net loss	(20,932)	(21,055)
Earnings Per Share, Basic, usd per share	$ (0.15)	$ (0.21)
Earnings Per Share, Diluted, usd per share	$ (0.20)	$ (0.21)
Weighted average common shares outstanding, basic	139,309	100,809
Weighted average common shares outstanding, diluted	145,323	100,809
Comprehensive loss	$ (20,932)	$ (21,055)