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Consolidated Statements of Cash Flows (USD $)
In Thousands, unless otherwise specified
12 Months Ended
Dec. 31, 2012
Dec. 31, 2011
Dec. 31, 2010
Operating activities:      
Net loss $ (47,386) $ (83,903) $ (73,564)
Adjustments to reconcile net loss to net cash used in operating activities:      
Stock-based compensation 6,157 4,809 2,507
Depreciation and amortization 1,599 1,584 1,428
Amortization of debt issuance costs and non-cash interest 2,017 1,793 1,582
Change in fair value of warrant liabilities (11,811) (445) (6,725)
Change in fair value of embedded derivatives 147 240 0
Beneficial conversion feature from issuance of convertible notes 0 0 4,696
Loss on disposal and impairment of property and equipment 9 0 2
Changes in operating assets and liabilities:      
Trade accounts receivable (730) (439) (4,474)
Inventory 3,890 1,517 (5,133)
Prepaid expenses and other current assets 163 24 537
Other assets 11 338 (3,976)
Accounts payable and accrued expenses 2,283 4,955 10,866
Deferred rent (89) (57) (48)
Deferred revenue (8,462) (10,887) 350
Net cash used in operating activities (52,202) (80,471) (71,952)
Investing activities:      
Purchases of property and equipment (293) (617) (3,442)
Net cash used in investing activities (293) (617) (3,442)
Financing activities:      
Proceeds from convertible notes, net of issuance costs 0 0 14,957
Proceeds from borrowings of debt and revolving credit facility, net of issuance costs 9,900 39,124 31,072
Payments on borrowings of debt (25,000) (825) (18,178)
Payments on revolving credit facility (15,051) (9,477) 0
Proceeds from exercise of common stock options 33 92 71
Proceeds from issuance of common stock and common stock warrants, net of issuance costs 67,316 59,527 51,733
Net cash provided by financing activities 37,198 88,441 79,655
Net (decrease) increase in cash and cash equivalents (15,297) 7,353 4,261
Cash and cash equivalents at beginning of period 56,525 49,172 44,911
Cash and cash equivalents at end of period 41,228 56,525 49,172
Supplemental disclosure of cash flow information:      
Cash paid for interest 5,284 4,186 2,403
Noncash investing and financing activities:      
Warrants issued in connection with public offering 20,959 0 0
Asset retirement obligation 286 0 0
Warrants issued in connection with debt 0 866 0
Embedded derivatives related to debt 0 605 0
Purchase of property and equipment in accounts payable 0 123 126
Vesting of early exercised stock options 0 15 59
Conversion of convertible preferred stock to common stock at initial public offering 0 0 149,312
Conversion of convertible notes and related interest to common stock, net of issuance costs 0 0 15,477
Reclassification of convertible preferred stock warrants to common stock warrants 0 0 743
Acquisition of leasehold paid by landlord $ 0 $ 0 $ 305