Cash and Cash Equivalents, and Marketable Securities - Amortized Cost and Fair Value of Cash, Cash Equivalents and Marketable Securities (Details) - USD ($) $ in Thousands	Dec. 31, 2021	Dec. 31, 2020
Cash and Cash Equivalents [Line Items]
Cash	$ 32,852	$ 23,887
Total cash and cash equivalents	101,180	166,916
Amortized Cost	200,548	338,004
Gross Unrealized Gains	0	190
Gross Unrealized Losses	(13)	(1)
Marketable securities	200,535	338,193
Total cash and cash equivalents and marketable securities	301,728	504,920
Total cash, cash equivalents and marketable securities at fair value	301,715	505,109
Money market funds
Cash and Cash Equivalents [Line Items]
Cash equivalents	29,991	80,986
Commercial paper
Cash and Cash Equivalents [Line Items]
Cash equivalents	35,337	61,043
Amortized Cost	141,718	210,986
Gross Unrealized Gains	0	0
Gross Unrealized Losses	0	0
Marketable securities	141,718	210,986
Certificates of deposit
Cash and Cash Equivalents [Line Items]
Cash equivalents	3,000	1,000
Amortized Cost	32,253	44,480
Gross Unrealized Gains	0	0
Gross Unrealized Losses	0	0
Marketable securities	32,253	44,480
U.S. Treasuries
Cash and Cash Equivalents [Line Items]
Amortized Cost		43,050
Gross Unrealized Gains		1
Gross Unrealized Losses		(1)
Marketable securities		43,050
U.S. Government-sponsored enterprises debt securities
Cash and Cash Equivalents [Line Items]
Amortized Cost	6,200	6,200
Gross Unrealized Gains	0	17
Gross Unrealized Losses	0	0
Marketable securities	6,200	6,217
Corporate debt securities
Cash and Cash Equivalents [Line Items]
Amortized Cost	20,377	33,288
Gross Unrealized Gains	0	172
Gross Unrealized Losses	(13)	0
Marketable securities	$ 20,364	$ 33,460