CONSOLIDATED BALANCE SHEETS - USD ($) $ in Thousands	Dec. 31, 2021	Dec. 31, 2020
Current assets:
Cash and cash equivalents	$ 101,180	$ 166,916
Marketable securities	200,535	338,193
Accounts receivable, net	10,139	3,824
Inventory	5,492	1,026
Prepaid expenses	12,487	7,279
Other current assets	24,735	4,936
Total current assets	354,568	522,174
Property and equipment, net	7,197	8,724
Operating lease right-of-use assets	6,605	7,748
Intangible asset, net	90,673	98,558
Goodwill	6,234	6,234
Other non-current assets	3,212	7,692
Total assets	468,489	651,130
Current liabilities:
Accounts payable	21,998	11,945
Accrued and other current liabilities	55,413	54,964
Deferred revenue, current	5,089	5,318
Current portion of operating lease liabilities	1,694	1,688
Current portion of contingent consideration	13,500	8,800
Total current liabilities	97,694	82,715
Deferred revenue, non-current	3,257	5,479
Operating lease liabilities, net of current portion	8,617	10,314
Contingent consideration, net of current portion	21,785	33,600
Convertible debt	158,165	149,353
Total liabilities	289,518	281,461
Commitments and contingencies (Note 12)
Stockholders’ equity:
Preferred stock, $0.001 par value; 10,000 shares authorized, none issued and outstanding	0	0
Common stock, $0.001 par value; 200,000 and 100,000 shares authorized and 56,095 and 55,736 shares issued and outstanding at December 31, 2021 and 2020, respectively	56	56
Additional paid-in capital	1,731,153	1,694,524
Accumulated other comprehensive loss	15	(71)
Accumulated deficit	(1,552,253)	(1,324,840)
Total stockholders’ equity	178,971	369,669
Total liabilities and stockholders’ equity	$ 468,489	$ 651,130