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CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS (Unaudited) - USD ($)
shares in Thousands, $ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2021
Sep. 30, 2020
Sep. 30, 2021
Sep. 30, 2020
Income Statement [Abstract]        
Net product sales $ 21,398 $ 1,520 $ 51,269 $ 1,520
Collaboration revenue 1,212 1,340 3,813 3,621
Total revenues 22,610 2,860 55,082 5,141
Costs and expenses:        
Cost of product sales (excluding amortization of intangible asset) 1,294 140 3,192 140
Research and development 33,255 34,425 100,868 102,038
Selling, general and administrative 39,559 24,583 104,713 70,332
Intangible asset amortization 1,972 1,971 5,914 1,971
Acquired in-process research and development costs 0 1,500 0 4,500
Change in fair value of contingent consideration 400 1,800 1,500 6,100
Total costs and expenses 76,480 64,419 216,187 185,081
Loss from operations (53,870) (61,559) (161,105) (179,940)
Other income (expense), net:        
Interest income 85 934 579 2,504
Interest expense (3,848) 0 (11,373) 0
Other, net (371) 536 (631) 20,798
Total other (expense) income, net (4,134) 1,470 (11,425) 23,302
Loss before income taxes (58,004) (60,089) (172,530) (156,638)
Income tax benefit 0 0 0 (17,425)
Net loss $ (58,004) $ (60,089) $ (172,530) $ (139,213)
Net loss per share, basic and diluted        
Net loss per share, basic (in dollars per share) $ (1.04) $ (1.08) $ (3.09) $ (2.62)
Net loss per share, diluted (in dollars per share) $ (1.04) $ (1.08) $ (3.09) $ (2.62)
Weighted average number of shares used in the calculation of basic net loss per common share (in shares) 55,905 55,548 55,831 53,039
Weighted average number of shares used in the calculation of diluted net loss per common share (in shares) 55,905 55,548 55,831 53,039