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CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS (Unaudited) - USD ($)
shares in Thousands, $ in Thousands
3 Months Ended 6 Months Ended
Jun. 30, 2021
Jun. 30, 2020
Jun. 30, 2021
Jun. 30, 2020
Income Statement [Abstract]        
Net product sales $ 17,523 $ 0 $ 29,871 $ 0
Collaboration revenue 1,266 1,032 2,601 2,281
Total revenues 18,789 1,032 32,472 2,281
Costs and expenses:        
Cost of product sales (excluding amortization of intangible asset) 1,222 0 1,898 0
Research and development 36,644 34,373 67,613 67,613
Selling, general and administrative 33,883 24,431 65,154 45,749
Intangible asset amortization 1,971 0 3,942 0
Acquired in-process research and development costs 0 1,500 0 3,000
Change in fair value of contingent consideration 500 12,200 1,100 4,300
Total costs and expenses 74,220 72,504 139,707 120,662
Loss from operations (55,431) (71,472) (107,235) (118,381)
Other income (expense), net:        
Interest income 186 880 494 1,968
Interest expense (3,789) 0 (7,525) 0
Other, net 138 (157) (260) 19,864
Total other (expense) income, net (3,465) 723 (7,291) 21,832
Loss before income taxes (58,896) (70,749) (114,526) (96,549)
Income tax benefit 0 (17,425) 0 (17,425)
Net loss $ (58,896) $ (53,324) $ (114,526) $ (79,124)
Net loss per share, basic and diluted        
Net loss per share, basic (in dollars per share) $ (1.05) $ (0.96) $ (2.05) $ (1.53)
Net loss per share, diluted (in dollars per share) $ (1.05) $ (0.96) $ (2.05) $ (1.53)
Weighted average number of shares used in the calculation of basic net loss per common share (in shares) 55,836 55,355 55,794 51,770
Weighted average number of shares used in the calculation of diluted net loss per common share (in shares) 55,836 55,355 55,794 51,770