CONSOLIDATED STATEMENTS OF OPERATIONS - USD ($) shares in Thousands		12 Months Ended
		Dec. 31, 2020	Dec. 31, 2019	Dec. 31, 2018
Revenues:
Net product sales		$ 9,587,000	$ 0	$ 0
Collaboration revenue		4,056,000	3,648,000	0
Total revenues		13,643,000	3,648,000	0
Operating costs and expenses:
Cost of product sales (excluding intangible asset amortization)		542,000	0	0
Research and development		138,002,000	115,639,000	100,925,000
Selling, general and administrative		99,574,000	60,792,000	38,950,000
Intangible asset amortization		3,942,000	0	0
Acquired in-process research and development and related costs		10,700,000	251,438,000	0
Change in fair value of contingent consideration		8,600,000	5,600,000	1,300,000
Total operating expenses		261,360,000	433,469,000	141,175,000
Loss from operations		(247,717,000)	(429,821,000)	(141,175,000)
Other income (expense):
Interest income		2,891,000	9,804,000	7,170,000
Interest expense		(3,759,000)	(2,000)	(6,000)
Other income, net		21,777,000	516,000	10,295,000
Loss from continuing operations before income taxes		(226,808,000)	(419,503,000)	(123,716,000)
Income tax benefit		(17,425,000)	0	0
Loss from continuing operations		(209,383,000)	(419,503,000)	(123,716,000)
Loss from discontinued operations		0	0	(198,000)
Net loss		$ (209,383,000)	$ (419,503,000)	$ (123,914,000)
Net loss per share, basic and diluted (in dollars per share)	[1]	$ (3.90)	$ (9.74)	$ (3.27)
Weighted average common shares outstanding, basic and diluted (shares)		53,706	43,078	37,884

[1] Net loss per share for both continuing operations and discontinued operations, basic and diluted, was the same for all periods presented.