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Condensed Consolidated Statements of Operations (Unaudited) - USD ($)
shares in Thousands, $ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2020
Sep. 30, 2019
Sep. 30, 2020
Sep. 30, 2019
Income Statement [Abstract]        
Net product sales $ 1,520 $ 0 $ 1,520 $ 0
Collaboration revenue 1,340 630 3,621 1,699
Total revenues 2,860 630 5,141 1,699
Costs and expenses:        
Cost of product sales (excluding amortization of intangible asset) 140 0 140 0
Research and development 34,425 28,372 102,038 79,820
Selling, general and administrative 24,583 15,762 70,332 42,139
Amortization of intangible asset 1,971 0 1,971 0
Acquired in-process research and development and acquisition-related costs 1,500 249,437 4,500 249,437
Change in fair value of contingent consideration 1,800 400 6,100 2,700
Total costs and expenses 64,419 293,971 185,081 374,096
Loss from operations (61,559) (293,341) (179,940) (372,397)
Other income, net 934 481 20,798 433
Interest income, net 536 2,382 2,504 8,521
Loss before income taxes (60,089) (290,478) (156,638) (363,443)
Income tax benefit 0 0 (17,425) 0
Net loss $ (60,089) $ (290,478) $ (139,213) $ (363,443)
Net loss per share, basic and diluted        
Net loss per share, basic and diluted (in dollars per share) $ (1.08) $ (6.75) $ (2.62) $ (8.54)
Weighted average number of shares used in the calculation of basic and diluted net loss per common share (in shares) 55,548 43,029 53,039 42,577