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Stock-Based Compensation - Assumptions used in Black-Scholes Option-Pricing Model (Detail) - $ / shares
12 Months Ended
Dec. 31, 2019
Dec. 31, 2018
Dec. 31, 2017
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Weighted-average fair value of option on grant date (in usd per share) $ 32.64 $ 30.87 $ 7.43
Shares subject to outstanding common stock options      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Risk free interest rate, minimum (percent) 1.40% 2.30% 1.80%
Risk free interest rate, maximum (percent) 2.60% 3.00% 2.30%
Expected volatility, minimum (percent) 73.50% 80.10% 75.10%
Expected volatility, maximum (percent) 82.30% 85.20% 85.80%
Expected dividend yield (percent) 0.00% 0.00% 0.00%
Shares subject to outstanding common stock options | Minimum      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Expected term 5 years 3 months 18 days 5 years 3 months 18 days 5 years 1 month 6 days
Shares subject to outstanding common stock options | Maximum      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Expected term 6 years 1 month 6 days 6 years 1 month 6 days 6 years 1 month 6 days