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Selected Quarterly Financial Information (Unaudited) (Details) - USD ($) $ / shares in Units, $ in Thousands	3 Months Ended								12 Months Ended
	Dec. 31, 2018	Sep. 30, 2018	Jun. 30, 2018	Mar. 31, 2018	Dec. 31, 2017	Sep. 30, 2017	Jun. 30, 2017	Mar. 31, 2017	Dec. 31, 2018	Dec. 31, 2017	Dec. 31, 2016
Quarterly Financial Information Disclosure [Abstract]
Revenue	$ 0	$ 0	$ 0	$ 0	$ 0	$ 0	$ 7,125	$ 2,696
Loss from continuing operations	(22,433)	(42,264)	(28,839)	(30,180)	(39,783)	(42,660)	(22,453)	(21,126)	$ (123,716)	$ (126,022)	$ (69,634)
(Loss) income from discontinued operations	0	0	(198)	0	75	(134)	(555)	(181)	(198)	(795)	(1,021)
Net loss	$ (22,433)	$ (42,264)	$ (29,037)	$ (30,180)	$ (39,708)	$ (42,794)	$ (23,008)	$ (21,307)	$ (123,914)	$ (126,817)	$ (69,707)
Net loss per share, basic and diluted (in dollars per share)	$ (0.53)	$ (1.08)	$ (0.83)	$ (0.87)	$ (1.17)	$ (1.68)	$ (0.93)	$ (0.86)	$ (3.27)	$ (4.65)	$ (2.81)

Amount after tax of income (loss) from a discontinued operation attributable to the parent. Includes, but is not limited to, the income (loss) from operations during the phase-out period, gain (loss) on disposal, gain (loss) for reversal of write-down (write-down) to fair value, less cost to sell, and adjustments to a prior period gain (loss) on disposal.

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- Definition

The portion of profit or loss for the period, net of income taxes, which is attributable to the parent.

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