Condensed Consolidated Statements of Operations and Comprehensive Loss (Unaudited) - USD ($) shares in Thousands, $ in Thousands	3 Months Ended
	Mar. 31, 2018	Mar. 31, 2017
Revenue:
Contract manufacturing revenue	$ 0	$ 2,696
Costs and expenses:
Cost of contract manufacturing	0	2,487
Research and development	22,980	13,341
Selling, general and administrative	8,070	6,554
Asset impairment charges	0	813
Change in fair value of contingent consideration	0	600
Total costs and expenses	31,050	23,795
Loss from operations	(31,050)	(21,099)
Other income (expense):
Interest income	833	94
Interest expense	(6)	(671)
Change in fair value of common stock warrant liabilities	17	587
Other income (expense)	26	(20)
Total other income (expense)	870	(10)
Loss from continuing operations before income taxes	(30,180)	(21,109)
Income tax expense	0	(17)
Net loss from continuing operations	(30,180)	(21,126)
Loss from discontinued operations, net of taxes	0	(181)
Net loss	$ (30,180)	$ (21,307)
Net loss per share, basic and diluted:
Continuing operations (in dollars per share)	$ (0.87)	$ (0.85)
Discontinued operations (in dollars per share)	0.00	(0.01)
Total (in dollars per share)	$ (0.87)	$ (0.86)
Weighted average shares outstanding, basic and diluted (shares)	34,841	24,813
Statements of Comprehensive Income (Loss)
Comprehensive loss	$ (30,180)	$ (21,307)