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Stock-Based Compensation - Assumptions used in Black-Scholes Option-Pricing Model (Detail) - Stock Options
3 Months Ended
Mar. 31, 2018
Mar. 31, 2017
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]    
Risk free interest rate, minimum 2.30% 2.10%
Risk free interest rate, maximum 2.70% 2.30%
Expected volatility, minimum 84.20% 76.40%
Expected volatility, maximum 85.20% 76.60%
Expected dividend yield 0.00% 0.00%
Minimum    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]    
Expected term 6 years 6 years
Maximum    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]    
Expected term 6 years 1 month 6 years 1 month