Summarized Quarterly Data (Unaudited) (Details) - USD ($) $ / shares in Units, $ in Thousands	3 Months Ended								12 Months Ended
	Dec. 31, 2017	Sep. 30, 2017	Jun. 30, 2017	Mar. 31, 2017	Dec. 31, 2016	Sep. 30, 2016	Jun. 30, 2016	Mar. 31, 2016	Dec. 31, 2017	Dec. 31, 2016	Dec. 31, 2015
Quarterly Financial Information Disclosure [Abstract]
Revenue	$ 0	$ 0	$ 7,125	$ 2,696	$ 10,986	$ 6,570	$ 2,088	$ 9,206	$ 9,821	$ 28,850	$ 27,182
Loss from continuing operations	(39,783)	(42,660)	(22,453)	(21,126)	(23,602)	(16,618)	(18,246)	(10,220)	(126,022)	(69,634)	(57,605)
(Loss) income from discontinued operations	75	(134)	(555)	(181)	109	(379)	(582)	(169)	(795)	(1,021)	67,848
Net (loss)	$ (39,708)	$ (42,794)	$ (23,008)	$ (21,307)	$ (23,493)	$ (16,997)	$ (18,828)	$ (10,389)	(126,817)	(69,707)	26,144
Net (loss) per share, basic and diluted (in dollars per share)	$ (1.17)	$ (1.68)	$ (0.93)	$ (0.86)	$ (0.95)	$ (0.69)	$ (0.76)	$ (0.42)
Inventory write-down									2,232	0	0
Asset impairment charges					$ 8,400				$ 1,116	$ 8,431	$ 0