Condensed Consolidated Statements of Operations and Comprehensive Loss (Unaudited) - USD ($) shares in Thousands, $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2017	Jun. 30, 2016	Jun. 30, 2017	Jun. 30, 2016
Revenue:
Contract manufacturing revenue	$ 7,125	$ 1,986	$ 9,821	$ 11,192
Service and other product revenue	0	102	0	102
Total revenue	7,125	2,088	9,821	11,294
Costs and expenses:
Cost of contract manufacturing	8,242	2,136	10,729	10,011
Research and development	14,850	10,384	28,191	18,371
Selling, general and administrative	5,502	6,844	12,056	12,968
Impairment charges	107	0	920	0
Change in fair value of contingent consideration	500	1,300	1,100	2,600
Total costs and expenses	29,201	20,664	52,996	43,950
Loss from operations	(22,076)	(18,576)	(43,175)	(32,656)
Other income (expense):
Interest expense, net	(575)	(623)	(1,152)	(1,221)
Change in fair value of common stock warrant liabilities	153	977	740	5,504
Other income (expense)	29	(15)	9	(23)
Total other (expense) income	(393)	339	(403)	4,260
Loss from continuing operations before income taxes	(22,469)	(18,237)	(43,578)	(28,396)
Income tax benefit (expense)	16	(9)	(1)	(71)
Net loss from continuing operations	(22,453)	(18,246)	(43,579)	(28,467)
Net loss from discontinued operations	(555)	(582)	(736)	(751)
Net loss	$ (23,008)	$ (18,828)	$ (44,315)	$ (29,218)
Net loss per share, basic and diluted:
Continuing operations (in dollars per share)	$ (0.90)	$ (0.74)	$ (1.76)	$ (1.15)
Discontinued operations (in dollars per share)	(0.03)	(0.02)	(0.03)	(0.03)
Total (in dollars per share)	$ (0.93)	$ (0.76)	$ (1.79)	$ (1.18)
Weighted average shares outstanding, basic and diluted	24,822	24,777	24,817	24,774
Statements of Comprehensive Income (Loss)
Comprehensive loss	$ (23,008)	$ (18,828)	$ (44,315)	$ (29,218)