Stock-Based Compensation (Tables)

6 Months Ended

Jun. 30, 2017

Disclosure of Compensation Related Costs, Share-based Payments [Abstract]

Assumptions used in the Black-Scholes Option-Pricing Model

	Three Months Ended June 30,		Six Months Ended June 30,
	2017	2016	2017	2016
Risk free interest rate	1.9% to 2.0%	1.2%	1.9% to 2.3%	1.2% to 1.4%
Expected term	5.1 to 6.1 years	6.0 to 6.1 years	5.1 to 6.1 years	6.0 to 6.1 years
Expected volatility	76.0% to 76.3%	78.1%	76.0% to 76.6%	77.8% to 78.1%
Expected dividend yield	—%	—%	—%	—%

Stock-Based Compensation Expense

The following table summarizes the components of total stock-based compensation expense included in the condensed consolidated statements of operations (in thousands):

	Three Months Ended June 30,					Six Months Ended June 30,
	2017			2016		2017		2016
Cost of contract manufacturing	$	(6	)	$	94	$	71	$	196
Research and development	502			493		1,019		917
Selling, general and administrative	635			1,187		1,714		2,149
Total	$	1,131		$	1,774	$	2,804	$	3,262