Condensed Consolidated Statements of Operations and Comprehensive Loss (Unaudited) - USD ($) shares in Thousands, $ in Thousands	3 Months Ended
	Mar. 31, 2017	Mar. 31, 2016
Revenue:
Contract manufacturing revenue	$ 2,696	$ 9,206
Costs and expenses:
Cost of contract manufacturing	2,487	7,804
Royalty expense	0	71
Research and development	13,341	7,987
Selling, general and administrative	6,554	6,124
Impairment charges	813	0
Change in fair value of contingent consideration	600	1,300
Total costs and expenses	23,795	23,286
Loss from operations	(21,099)	(14,080)
Other income (expense):
Interest expense, net	(577)	(598)
Change in fair value of common stock warrant liabilities	587	4,527
Other expense	(20)	(7)
Total other (expense) income	(10)	3,922
Loss from continuing operations before income taxes	(21,109)	(10,158)
Income tax expense	(17)	(62)
Net loss from continuing operations	(21,126)	(10,220)
Net loss from discontinued operations	(181)	(169)
Net loss	$ (21,307)	$ (10,389)
Net loss per share, basic and diluted:
Continuing operations (in dollars per share)	$ (0.85)	$ (0.41)
Discontinued operations (in dollars per share)	(0.01)	(0.01)
Total (in dollars per share)	$ (0.86)	$ (0.42)
Weighted average shares outstanding, basic and diluted (shares)	24,813	24,722
Statements of Comprehensive Income (Loss)
Comprehensive loss	$ (21,307)	$ (10,389)