Income Taxes (Tables)

12 Months Ended

Dec. 31, 2016

Income Tax Disclosure [Abstract]

Summary of Unrecognized Tax Benefits

The following table summarizes the activity related to the Company’s unrecognized tax benefits (in thousands):

	December 31,
	2016		2015		2014
Beginning balance of unrecognized tax benefits	$	1,132	$	1,019	$	899
Gross increases based on tax positions related to current year	116		113		120
Gross increases based on tax positions related to prior year	—		—		—
Settlements with taxing authorities	—		—		—
Expiration of statute of limitations	—		—		—
Ending balance of unrecognized tax benefits	$	1,248	$	1,132	$	1,019

Schedule of Domestic and Foreign Components of Loss before Provision for Income Taxes

For financial reporting purposes, (loss) income from continuing operations before income taxes includes the following components (in thousands):

	December 31,
	2016			2015			2014
United States	(24,285		)	(40,845		)	62,479
Foreign	(45,349		)	(16,760		)	(908		)
Total	$	(69,634	)	$	(57,605	)	$	61,571

Reconciliation of Income Tax to Expense (Benefit)

The reconciliation of income tax from continuing operations computed at the Federal statutory tax rate to the (benefit) expense for income taxes were as follows (in thousands):

	December 31,
	2016			2015			2014
Tax at statutory rate	$	(23,675	)	$	(19,586	)	$	20,934
State taxes, net of federal benefit	(65		)	(691		)	1,499
Change in valuation allowance	16,024			(14,042		)	(12,968		)
Valuation allowance adjustment for continuing operations	—			15,498			—
Permanent interest disallowed	(1,832		)	375			(8,608		)
Foreign rate change - Impact on Deferred Taxes	521			(1,993		)	—
Other permanent differences	1,307			114			1,226
Research and development tax credits	(145		)	(1,060		)	(1,387		)
State tax rate benefit	578			2,181			(503		)
Foreign rate differential	6,122			2,550			—
Credits and other	217			753			(109		)
Tax (benefit) expense	$	(948	)	$	(15,901	)	$	84

Schedule of Deferred Tax Assets

	December 31,
	2016			2015
Deferred tax assets:
Net operating losses	$	90,543		$	72,402
Capitalized research and development	4,504			5,768
Accrued expenses	1,240			1,266
Research and development credits	4,596			4,451
Accrued product returns	34			324
Inventory reserve and UNICAP	175			1,063
Amortization	1,680			1,998
Depreciation	1,533			—
Deferred revenue	475			3,494
Other, net	7,542			6,432
Total deferred tax assets	112,322			97,198
Less valuation allowance	(112,322		)	(96,298		)
Net deferred tax assets	—			900
Deferred tax liabilities:
Depreciation	—			(900		)
IPR&D	(17,425		)	(18,450		)
Total deferred tax liabilities	(17,425		)	(19,350		)
Net deferred tax liability	$	(17,425	)	$	(18,450	)