Consolidated Statements of Operations and Comprehensive Income (Loss) - USD ($) shares in Thousands, $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2016	Sep. 30, 2015	Sep. 30, 2016	Sep. 30, 2015
Revenue:
Contract manufacturing revenue	$ 6,345	$ 8,860	$ 17,537	$ 19,044
Service and other product revenue	225	260	327	2,057
Total revenue	6,570	9,120	17,864	21,101
Operating expense:
Cost of contract manufacturing	6,391	7,780	16,256	17,506
Royalty expense	78	106	224	249
Research and development	10,076	7,919	28,447	19,310
Selling, general and administrative	6,538	5,696	19,506	19,547
Change in fair value of contingent purchase consideration	200	(300)	2,800	(1,900)
Total operating expense	23,283	21,201	67,233	54,712
Loss from operations	(16,713)	(12,081)	(49,369)	(33,611)
Other income (expense):
Interest expense	(567)	(718)	(1,788)	(2,259)
Loss on short-term investments	0	5,485	0	5,485
Change in fair value of warrant liabilities	(356)	(296)	5,148	(861)
Other (income) expense	25	103	2	(55)
Total other income (expense)	(898)	(6,396)	3,362	(8,660)
Net loss from continuing operations before income taxes	(17,611)	(18,477)	(46,007)	(42,271)
Income tax benefit	993	5,496	922	12,428
Net loss from continuing operations	(16,618)	(12,981)	(45,085)	(29,843)
Net income (loss) from discontinued operations	(379)	(1,635)	(1,130)	64,829
Net income	$ (16,997)	$ (14,616)	$ (46,215)	$ 34,986
Net income (loss) per share, basic and diluted: (1)
Continuing operations, usd per share	$ (0.67)	$ (0.57)	$ (1.82)	$ (1.47)
Discontinued operations, usd per share	(0.02)	(0.07)	(0.05)	3.19
Total, usd per share	$ (0.69)	$ (0.65)	$ (1.87)	$ 1.72
Weighted average common shares outstanding, basic	24,791	22,613	24,780	20,332
Statements of Comprehensive Income (Loss)
Unrealized loss on available-for-sale securities	$ 0	$ (3,933)	$ 0	$ (5,485)
Reclassification of other-than-temporary loss on available-for-sale securities included in net income (loss)	0	5,485	0	5,485
Comprehensive income (loss)	$ (16,997)	$ (13,064)	$ (46,215)	$ 34,986