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Stock-Based Compensation - Assumptions used in Black-Scholes Option-Pricing Model (Detail) - Stock Options
3 Months Ended 9 Months Ended
Sep. 30, 2016
Sep. 30, 2015
Sep. 30, 2016
Sep. 30, 2015
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Risk free interest rate, minimum 1.10% 1.60% 1.10% 1.50%
Risk free interest rate, maximum 1.30% 1.60% 1.40% 1.80%
Expected volatility rate 77.00%      
Expected volatility, minimum   77.60% 77.00% 76.70%
Expected volatility, maximum 78.10% 77.60% 78.10% 79.20%
Expected dividend yield 0.00% 0.00% 0.00% 0.00%
Minimum        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Expected term 5 years 1 month 6 years 1 month 5 years 1 month 5 years 1 month
Maximum        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Expected term 6 years 1 month 6 years 1 month 6 days 6 years 1 month 6 years 1 month