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Summarized Quarterly Data (Unaudited) (Details) - USD ($)
$ / shares in Units, $ in Thousands
3 Months Ended 12 Months Ended
Apr. 24, 2015
May. 16, 2014
Dec. 31, 2015
Sep. 30, 2015
Jun. 30, 2015
Mar. 31, 2015
Dec. 31, 2014
Sep. 30, 2014
Jun. 30, 2014
Mar. 31, 2014
Dec. 31, 2015
Dec. 31, 2014
Dec. 31, 2013
Quarterly Financial Information Disclosure [Abstract]                          
Revenue     $ 6,081 $ 9,120 $ 7,367 $ 4,614 $ 9,938 $ 4,883 $ 6,737 $ 7,389 $ 27,182 $ 28,947 $ 33,012
Gross profit     1,231 1,340 1,564 691 1,515 897 2,874 4,056      
Net loss from continuing operations     (11,862) (12,981) (6,696) (10,165) (9,636) (1,461) 77,536 (4,952) (57,605) 61,571 (72,601)
Net income (loss) from discontinued operations     3,019 (1,635) 79,160 (12,696) (11) (11) (15) (16) 67,848 (52,900) (8,255)
Net income (loss)     $ (8,843) $ (14,616) $ 72,464 $ (22,861) $ (21) $ (13) $ 63 $ (21) $ 26,144 $ 8,587 $ (80,856)
Net income (loss) per share, basic and diluted (in dollars per share)     $ (0.36) $ (0.65) $ 3.78 $ (1.19)              
Net income (loss) per share, basic (in dollars per share)             $ (1.09) $ (0.73) $ 3.59 $ (1.20) $ 1.22 $ 0.48 $ (5.96)
Net income (loss) per share, diluted (in dollars per share)             $ (1.09) $ (0.73) $ 3.59 $ (1.61) $ 1.22 $ 0.48 $ (5.96)
Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items]                          
Gain on sale of business                     $ 0 $ 79,980 $ 0
Impairment of long-lived assets                     0 (838) 0
Loss on extinguishment of debt   $ (1,254)                 0 1,254 0
Zohydro ER [Member]                          
Quarterly Financial Information Disclosure [Abstract]                          
Net income (loss) from discontinued operations                     67,848 (52,900) (8,255)
Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items]                          
Gain on sale of business     $ 2,323 $ 2,474 $ 75,575                
Income tax expense     3,472 5,496 $ 6,946           $ (14,060) $ 0 $ 0
Recognition of contingent consideration $ 14,060   $ 385                    
Impairment of long-lived assets       $ (5,485)                  
Sumavel DosePro [Member]                          
Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items]                          
Gain on sale of business                 $ 79,980        
Impairment of long-lived assets                 (838)        
Healthcare Royalty [Member]                          
Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items]                          
Loss on extinguishment of debt                 $ 1,254