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Consolidated Statement of Stockholders' Equity (Deficit) (Parenthetical) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2015
Dec. 31, 2013
Statement of Stockholders' Equity [Abstract]    
Issuance costs of common stock from July 2012 offering   $ 3,328
Issuance costs of common stock from November 2013 offering   4,529
Issuance costs of controlled equity offering   $ 371
Stock issuance costs $ 6,317