Common Stock Warrants	9 Months Ended
Sep. 30, 2015
Disclosure Common Stock Warrants Additional Informational [Abstract]
Common Stock Warrants	Common Stock Warrant Liability In July 2012, in connection with a public offering of common stock and warrants, the Company sold warrants to purchase 1,973,025 shares of common stock (including over-allotment purchase) and at September 30, 2015 warrants to purchase 1,901,931 shares of common stock are outstanding. The warrants are exercisable at an exercise price of $20.00 per share and will expire on July 27, 2017, which is five years from the date of issuance. As the warrants contain a cash settlement feature upon the occurrence of certain events that may be outside of the Company’s control, the warrants are recorded as a current liability and are marked to market at each reporting period (see Note 2). During the three and nine months ended September 30, 2015, no warrants to purchase shares of common stock were exercised that were classified as liabilities, and during the year ended December 31, 2014, warrants to purchase 58,156 shares of common stock were exercised. The Company recognized no proceeds from the exercise of these warrants during the three and nine months ended September 30, 2015 and $1,163,000 in proceeds from the exercise of warrants during the three and nine months ended September 30, 2014. The fair value of the warrants outstanding was approximately $5,840,000 and $4,978,000 as of September 30, 2015 and December 31, 2014, respectively. In July 2011, upon the closing of and in connection with the Healthcare Royalty financing agreement, the Company issued to Healthcare Royalty a warrant exercisable into 28,125 shares of common stock. The warrant is exercisable at $72.00 per share of common stock and has a term of ten years. As the warrant contains covenants where compliance with such covenants may be outside of the Company’s control, the warrant was recorded as a current liability and is marked to market at each reporting date (see Note 2). The fair value of the warrant was approximately $114,000 and $115,000 as of September 30, 2015 and December 31, 2014, respectively.

Common Stock Warrant Liability

In July 2012, in connection with a public offering of common stock and warrants, the Company sold warrants to purchase 1,973,025 shares of common stock (including over-allotment purchase) and at September 30, 2015 warrants to purchase 1,901,931 shares of common stock are outstanding. The warrants are exercisable at an exercise price of $20.00 per share and will expire on July 27, 2017, which is five years from the date of issuance. As the warrants contain a cash settlement feature upon the occurrence of certain events that may be outside of the Company’s control, the warrants are recorded as a current liability and are marked to market at each reporting period (see Note 2). During the three and nine months ended September 30, 2015, no warrants to purchase shares of common stock were exercised that were classified as liabilities, and during the year ended December 31, 2014, warrants to purchase 58,156 shares of common stock were exercised. The Company recognized no proceeds from the exercise of these warrants during the three and nine months ended September 30, 2015 and $1,163,000 in proceeds from the exercise of warrants during the three and nine months ended September 30, 2014. The fair value of the warrants outstanding was approximately $5,840,000 and $4,978,000 as of September 30, 2015 and December 31, 2014, respectively.

In July 2011, upon the closing of and in connection with the Healthcare Royalty financing agreement, the Company issued to Healthcare Royalty a warrant exercisable into 28,125 shares of common stock. The warrant is exercisable at $72.00 per share of common stock and has a term of ten years. As the warrant contains covenants where compliance with such covenants may be outside of the Company’s control, the warrant was recorded as a current liability and is marked to market at each reporting date (see Note 2). The fair value of the warrant was approximately $114,000 and $115,000 as of September 30, 2015 and December 31, 2014, respectively.