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Consolidated Statements of Cash Flows (USD $)
In Thousands, unless otherwise specified
3 Months Ended
Mar. 31, 2015
Mar. 31, 2014
Operating activities:    
Net loss for basic EPS $ (22,861)us-gaap_NetIncomeLoss $ (20,932)us-gaap_NetIncomeLoss
Adjustments to reconcile net loss to net cash used in operating activities:    
Stock-based compensation 1,871us-gaap_ShareBasedCompensation 2,507us-gaap_ShareBasedCompensation
Depreciation and amortization 393us-gaap_DepreciationDepletionAndAmortization 406us-gaap_DepreciationDepletionAndAmortization
Amortization of debt issuance costs and non-cash interest 257us-gaap_AmortizationOfFinancingCostsAndDiscounts 161us-gaap_AmortizationOfFinancingCostsAndDiscounts
Change in fair value of warrant liabilities (410)us-gaap_FairValueOptionChangesInFairValueGainLoss1 (8,269)us-gaap_FairValueOptionChangesInFairValueGainLoss1
Change in fair value of embedded derivatives 0us-gaap_DerivativeGainLossOnDerivativeNet 14us-gaap_DerivativeGainLossOnDerivativeNet
Change in fair value of contingent purchase consideration (1,000)us-gaap_BusinessCombinationContingentConsiderationArrangementsChangeInAmountOfContingentConsiderationLiability1 0us-gaap_BusinessCombinationContingentConsiderationArrangementsChangeInAmountOfContingentConsiderationLiability1
Changes in operating assets and liabilities:    
Trade accounts receivable 4,207us-gaap_IncreaseDecreaseInAccountsReceivable (5,015)us-gaap_IncreaseDecreaseInAccountsReceivable
Inventory, net (450)us-gaap_IncreaseDecreaseInInventories (4,918)us-gaap_IncreaseDecreaseInInventories
Prepaid expenses and other current assets (1,853)us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets 882us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets
Other assets (621)us-gaap_IncreaseDecreaseInOtherOperatingAssets (534)us-gaap_IncreaseDecreaseInOtherOperatingAssets
Accounts payable and accrued expenses 947us-gaap_IncreaseDecreaseInAccountsPayableAndAccruedLiabilities 6,937us-gaap_IncreaseDecreaseInAccountsPayableAndAccruedLiabilities
Deferred rent (26)zgnx_IncreaseDecreaseInDeferredRent (26)zgnx_IncreaseDecreaseInDeferredRent
Deferred revenue (2,401)us-gaap_IncreaseDecreaseInDeferredRevenue 5,963us-gaap_IncreaseDecreaseInDeferredRevenue
Net cash used in operating activities (21,947)us-gaap_NetCashProvidedByUsedInOperatingActivities (22,824)us-gaap_NetCashProvidedByUsedInOperatingActivities
Investing activities:    
Purchases of property and equipment (54)us-gaap_PaymentsToAcquirePropertyPlantAndEquipment (15)us-gaap_PaymentsToAcquirePropertyPlantAndEquipment
Net cash used in investing activities (54)us-gaap_NetCashProvidedByUsedInInvestingActivities (15)us-gaap_NetCashProvidedByUsedInInvestingActivities
Financing activities:    
Proceeds from revolving credit facility 1,450us-gaap_ProceedsFromSecuredLinesOfCredit 0us-gaap_ProceedsFromSecuredLinesOfCredit
Repayment of debt (343)us-gaap_RepaymentsOfDebt 0us-gaap_RepaymentsOfDebt
Proceeds from exercise of common stock options 3us-gaap_ProceedsFromIssuanceOrSaleOfEquity 1,502us-gaap_ProceedsFromIssuanceOrSaleOfEquity
Net cash provided by financing activities 1,110us-gaap_NetCashProvidedByUsedInFinancingActivities 1,502us-gaap_NetCashProvidedByUsedInFinancingActivities
Net (decrease) increase in cash and cash equivalents (20,891)us-gaap_CashAndCashEquivalentsPeriodIncreaseDecrease (21,337)us-gaap_CashAndCashEquivalentsPeriodIncreaseDecrease
Cash and cash equivalents at beginning of period 42,205us-gaap_CashAndCashEquivalentsAtCarryingValue 72,021us-gaap_CashAndCashEquivalentsAtCarryingValue
Cash and cash equivalents at end of period 21,314us-gaap_CashAndCashEquivalentsAtCarryingValue 50,684us-gaap_CashAndCashEquivalentsAtCarryingValue
Noncash investing and financing activities:    
Change in purchases of property and equipment in accounts payable $ 0us-gaap_CapitalExpendituresIncurredButNotYetPaid $ (310)us-gaap_CapitalExpendituresIncurredButNotYetPaid