Consolidated Statements of Operations and Comprehensive Income (Loss) (USD $) In Thousands, except Per Share data, unless otherwise specified	12 Months Ended
	Dec. 31, 2014	Dec. 31, 2013	Dec. 31, 2012
Revenue:
Net product revenue	$ 21,715	$ 31,699	$ 35,826
Contract manufacturing revenue	15,392	0	0
Contract revenue	0	0	8,462
Service and other revenue	3,424	1,313	38
Total revenue	40,531	33,012	44,326
Operating expenses:
Cost of goods sold	15,817	21,241	19,496
Cost of contract manufacturing	14,342	0	0
Royalty expense	1,718	1,242	1,353
Research and development	18,936	12,805	21,414
Selling, general and administrative	88,899	50,040	49,494
Restructuring	0	876	0
Impairment of long-lived assets	838	0	0
Net gain on sale of business	(79,980)	0	0
Total operating expenses	60,570	86,204	91,757
Loss from operations	(20,039)	(53,192)	(47,431)
Other income (expense):
Interest income	20	18	53
Interest expense	(3,090)	(6,610)	(10,313)
Loss on extinguishment of debt	(1,254)	0	0
Change in fair value of warrant liabilities	25,332	(21,927)	11,811
Change in fair value of embedded derivatives	(14)	759	(147)
Other income (expense)	7,716	96	(1,354)
Total other income (expense)	28,710	(27,664)	50
Net income (loss) before income taxes	8,671	(80,856)	(47,381)
Provision for income taxes	(84)	0	(5)
Net income (loss)	8,587	(80,856)	(47,386)
Net loss per share, basic and diluted (in dollars per share)	$ 0.06	$ (0.74)	$ (0.59)
Weighted-average shares outstanding, basic (in shares)	142,607	108,568	80,558
Weighted average common shares outstanding, diluted	145,046	108,568	80,558
Comprehensive income (loss)	$ 8,587	$ (80,856)	$ (47,386)