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Collaboration, License and Purchase Agreements - Narrative 2 (Details) (USD $)
0 Months Ended 12 Months Ended 1 Months Ended
Nov. 03, 2013
Altus Formulation Inc. Development and Option Agreement [Member]
Dec. 31, 2013
Altus Formulation Inc. Development and Option Agreement [Member]
Dec. 31, 2011
Durect Development and License Agreement [Member]
Dec. 31, 2011
Durect Development and License Agreement [Member]
Minimum [Member]
Dec. 31, 2011
Durect Development and License Agreement [Member]
Research and Development Expense [Member]
Dec. 31, 2013
Alkermes License Agreement (formerly Elan Pharma International Limited) [Member]
Oct. 31, 2013
Alkermes License Agreement (formerly Elan Pharma International Limited) [Member]
Other Assets [Member]
May 31, 2012
Alkermes License Agreement (formerly Elan Pharma International Limited) [Member]
Research and Development Expense [Member]
Aug. 30, 2011
Alkermes License Agreement (formerly Elan Pharma International Limited) [Member]
Research and Development Expense [Member]
Nov. 30, 2007
Alkermes License Agreement (formerly Elan Pharma International Limited) [Member]
Research and Development Expense [Member]
Research and Development Arrangement, Contract to Perform for Others [Line Items]                    
Non Refundable Up Front Fee Payment $ 750,000                  
Maximum Additional Payments On Achievement Of Series Of Milestones   3,500,000                
Agreement termination notice period   30 days       12 months        
Non-refundable up-front payment         2,250,000         500,000
Milestone payments made             2,750,000 1,000,000 750,000  
Minimum future milestone payments     103,000,000              
Annual external development expense obligation       $ 1,000,000            
External development expense obligation period     12 months              
Royalty agreement term     15 years     15 years        
Automatic extension of arrangement term           3 years