Collaboration, License and Purchase Agreements - Narrative (Detail) (USD $)	12 Months Ended					0 Months Ended	12 Months Ended	0 Months Ended	12 Months Ended	1 Months Ended		12 Months Ended					1 Months Ended					12 Months Ended
	Dec. 31, 2013	Dec. 31, 2012	Dec. 31, 2011	Dec. 31, 2013 Mallinckrodt LLC Co-Promotion Agreement [Member]	Dec. 31, 2012 Mallinckrodt LLC Co-Promotion Agreement [Member]	Jun. 27, 2013 Valeant Pharmaceuticals North America LLC Co-Promotions Agreement [Member]	Dec. 31, 2013 Valeant Pharmaceuticals North America LLC Co-Promotions Agreement [Member]	Nov. 02, 2012 Alkermes Commerical Manufacturing And Supply Agreement [Member]	Dec. 31, 2013 Alkermes Commerical Manufacturing And Supply Agreement [Member]	Aug. 31, 2012 Astellas Pharma Us Inc Co Promotion Agreement [Member]	Jul. 31, 2009 Astellas Pharma Us Inc Co Promotion Agreement [Member]	Dec. 31, 2013 Astellas Pharma Us Inc Co Promotion Agreement [Member]	Dec. 31, 2012 Astellas Pharma Us Inc Co Promotion Agreement [Member]	Dec. 31, 2011 Astellas Pharma Us Inc Co Promotion Agreement [Member]	Jul. 31, 2013 Astellas Pharma Us Inc Co Promotion Agreement [Member]	Dec. 20, 2011 Astellas Pharma Us Inc Co Promotion Agreement [Member]	Jul. 31, 2009 Astellas Pharma Us Inc Co Promotion Agreement [Member] Minimum [Member]	Jul. 31, 2009 Astellas Pharma Us Inc Co Promotion Agreement [Member] Maximum [Member]	Dec. 31, 2013 Aradigm Corporation Asset Purchase Agreement [Member]	Feb. 28, 2010 Aradigm Corporation Asset Purchase Agreement [Member]	Aug. 31, 2006 Aradigm Corporation Asset Purchase Agreement [Member]	Dec. 31, 2013 Aradigm Corporation Asset Purchase Agreement [Member]	Dec. 31, 2012 Aradigm Corporation Asset Purchase Agreement [Member]	Dec. 31, 2011 Aradigm Corporation Asset Purchase Agreement [Member]
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Incurred service fee expenses				$ 1,035,000	$ 161,000							$ 0	$ 1,756,000	$ 6,657,000
Additional term increments						12 months
Agreement termination notice period						6 months
Agreement termination notice period, net sales contingent						30 days
Agreement termination notice period, change of control contingent						90 days
Service and other revenue	1,313,000	38,000	0				1,109,000
Monthly forecast period								18 months	18 months
Annual forecast period								3 years
Order period after forecast submission								4 months
Percentage required to purchase								75.00%
Percentage to be purchased from supplier								100.00%
Non-refundable up-front payment											2,000,000
Milestone payments received											18,000,000
Service fee rate																	45.00%	55.00%
Deferred agreement payments											20,000,000
Amortizing the upfront and milestone payments as contract revenue recognized												0	8,462,000	7,165,000
Annual tail payment liability										742,000		1,131,000	2,795,000			5,291,000
Tail Payment Liability, First Payment															2,000,000
Interest expense												368,000	550,000
Service fee reduction										1,500,000			1,924,000
Present value of the service fee receivable and tail payment													1,924,000
Recognized shared marketing expense												0	253,000	1,663,000
Payment to acquire tangible and intangible assets																					4,000,000
Milestone payment to acquire tangible and intangible assets																				4,000,000
Royalty rate																			3.00%			3.00%
Royalty expense	1,242,000	1,353,000	1,205,000																			1,242,000	1,353,000	1,205,000
Expected amortization expense, 2014																			286,000			286,000
Expected amortization expense, 2015																			286,000			286,000
Expected amortization expense, 2016																			286,000			286,000
Expected amortization expense, 2017																			286,000			286,000
Expected amortization expense, 2018																			286,000			286,000
Expected amortization expense, thereafter																			$ 2,571,000			$ 2,571,000