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Summary of Significant Accounting Policies - Assets and Liabilities Measured at Fair Value on a Recurring Basis (Detail) (USD $)
In Thousands, unless otherwise specified
12 Months Ended
Dec. 31, 2013
Maximum [Member]
Dec. 31, 2013
Embedded Derivative Liabilities [Member]
Dec. 31, 2012
Embedded Derivative Liabilities [Member]
Dec. 31, 2013
Fair Value, Measurements, Recurring [Member]
Quoted Prices in Active Markets for Identical Assets (Level 1) [Member]
Common Stock Warrant Liabilities [Member]
Dec. 31, 2012
Fair Value, Measurements, Recurring [Member]
Quoted Prices in Active Markets for Identical Assets (Level 1) [Member]
Common Stock Warrant Liabilities [Member]
Dec. 31, 2013
Fair Value, Measurements, Recurring [Member]
Quoted Prices in Active Markets for Identical Assets (Level 1) [Member]
Embedded Derivative Liabilities [Member]
Dec. 31, 2012
Fair Value, Measurements, Recurring [Member]
Quoted Prices in Active Markets for Identical Assets (Level 1) [Member]
Embedded Derivative Liabilities [Member]
Dec. 31, 2013
Fair Value, Measurements, Recurring [Member]
Quoted Prices in Active Markets for Identical Assets (Level 1) [Member]
Money market fund shares [Member]
Dec. 31, 2012
Fair Value, Measurements, Recurring [Member]
Quoted Prices in Active Markets for Identical Assets (Level 1) [Member]
Money market fund shares [Member]
Dec. 31, 2013
Fair Value, Measurements, Recurring [Member]
Significant Other Observable Inputs (Level 2) [Member]
Common Stock Warrant Liabilities [Member]
Dec. 31, 2012
Fair Value, Measurements, Recurring [Member]
Significant Other Observable Inputs (Level 2) [Member]
Common Stock Warrant Liabilities [Member]
Dec. 31, 2013
Fair Value, Measurements, Recurring [Member]
Significant Other Observable Inputs (Level 2) [Member]
Embedded Derivative Liabilities [Member]
Dec. 31, 2012
Fair Value, Measurements, Recurring [Member]
Significant Other Observable Inputs (Level 2) [Member]
Embedded Derivative Liabilities [Member]
Dec. 31, 2013
Fair Value, Measurements, Recurring [Member]
Significant Other Observable Inputs (Level 2) [Member]
Money market fund shares [Member]
Dec. 31, 2012
Fair Value, Measurements, Recurring [Member]
Significant Other Observable Inputs (Level 2) [Member]
Money market fund shares [Member]
Dec. 31, 2013
Fair Value, Measurements, Recurring [Member]
Significant Unobservable Inputs (Level 3) [Member]
Common Stock Warrant Liabilities [Member]
Dec. 31, 2012
Fair Value, Measurements, Recurring [Member]
Significant Unobservable Inputs (Level 3) [Member]
Common Stock Warrant Liabilities [Member]
Dec. 31, 2013
Fair Value, Measurements, Recurring [Member]
Significant Unobservable Inputs (Level 3) [Member]
Embedded Derivative Liabilities [Member]
Dec. 31, 2012
Fair Value, Measurements, Recurring [Member]
Significant Unobservable Inputs (Level 3) [Member]
Embedded Derivative Liabilities [Member]
Dec. 31, 2013
Fair Value, Measurements, Recurring [Member]
Significant Unobservable Inputs (Level 3) [Member]
Money market fund shares [Member]
Dec. 31, 2012
Fair Value, Measurements, Recurring [Member]
Significant Unobservable Inputs (Level 3) [Member]
Money market fund shares [Member]
Dec. 31, 2013
Fair Value, Measurements, Recurring [Member]
Estimate of Fair Value, Fair Value Disclosure [Member]
Common Stock Warrant Liabilities [Member]
Dec. 31, 2012
Fair Value, Measurements, Recurring [Member]
Estimate of Fair Value, Fair Value Disclosure [Member]
Common Stock Warrant Liabilities [Member]
Dec. 31, 2013
Fair Value, Measurements, Recurring [Member]
Estimate of Fair Value, Fair Value Disclosure [Member]
Embedded Derivative Liabilities [Member]
Dec. 31, 2012
Fair Value, Measurements, Recurring [Member]
Estimate of Fair Value, Fair Value Disclosure [Member]
Embedded Derivative Liabilities [Member]
Dec. 31, 2013
Fair Value, Measurements, Recurring [Member]
Estimate of Fair Value, Fair Value Disclosure [Member]
Money market fund shares [Member]
Dec. 31, 2012
Fair Value, Measurements, Recurring [Member]
Estimate of Fair Value, Fair Value Disclosure [Member]
Money market fund shares [Member]
Assets                                                      
Assets measured at fair value on a recurring basis               $ 69,120 [1] $ 37,605 [1]         $ 0 [1] $ 0 [1]         $ 0 [1] $ 0 [1]         $ 69,120 [1] $ 37,605 [1]
Liabilities                                                      
Liabilities measured at fair value on a recurring basis   $ 233 $ 992 $ 0 [2] $ 0 $ 0 [3] $ 0 [3]     $ 0 [2] $ 0 $ 0 [3] $ 0 [3]     $ 31,341 [2] $ 9,493 $ 233 $ 992     $ 31,341 [2] $ 9,493 $ 233 [3] $ 992 [3]    
Volatility rate 40.00%                                                    
[1] Cash equivalents are comprised of money market fund shares and are included as a component of cash and cash equivalents on the consolidated balance sheet.
[2] Common stock warrant liabilities include liabilities associated with warrants issued in connection with the Company's July 2012 public offering of common stock and warrants (see Note 8) and warrants issued in connection with the Healthcare Royalty financing agreement (see Note 7), which are measured at fair value using the Black-Scholes option pricing valuation model. The assumptions used in the Black-Scholes option pricing valuation model for both common stock warrant liabilities were: (a) a risk-free interest rate based on the rates for U.S. Treasury zero-coupon bonds with maturities similar to those of the remaining contractual term of the warrants; (b) an assumed dividend yield of zero based on the Company’s expectation that it will not pay dividends in the foreseeable future; (c) an expected term based on the remaining contractual term of the warrants; and (d) given the Company’s lack of relevant historical data due to the Company’s limited historical experience, an expected volatility based upon the Company's historical volatility, supplemented with historical volatility of comparable companies whose share prices have been publicly available for a sufficient period of time. The significant unobservable input used in measuring the fair value of the common stock warrant liabilities associated with the Healthcare Royalty financing agreement is the expected volatility. Significant increases in volatility would result in a higher fair value measurement. The following additional assumptions were used in the Black-Scholes option pricing valuation model to measure the fair value of the warrants sold in the July 2012 public offering: (a) management's projections regarding the probability of the occurrence of an extraordinary event and the timing of such event; and for the valuation scenario in which an extraordinary event occurs that is not an all cash transaction or an event whereby a public acquirer would assume the warrants, (b) an expected volatility rate using the Company's historical volatility, supplemented with historical volatility of comparable companies, through the projected date of public announcement of an extraordinary transaction, blended with a rate equal to the lesser of 40% and the 180-day volatility rate obtained from the HVT function on Bloomberg as of the trading day immediately following the public announcement of an extraordinary transaction. The significant unobservable inputs used in measuring the fair value of the common stock warrant liabilities associated with the July 2012 public offering are the expected volatility and the probability of the occurrence of an extraordinary event. Significant increases in volatility would result in a higher fair value measurement and significant increases in the probability of an extraordinary event occurring would result in a significantly lower fair value measurement.
[3] Embedded derivatives are measured at fair value using various discounted cash flow valuation models are included as a component of other long-term liabilities on the consolidated balance sheets. The assumptions used in the discounted cash flow valuation models include: (a) management's revenue projections and a revenue sensitivity analysis based on possible future outcomes; (b) probability weighted net cash flows based on the likelihood of Healthcare Royalty receiving interest payments over the term of the financing agreement; (c) probability of bankruptcy; (d) weighted average cost of capital that included the addition of a company specific risk premium to account for uncertainty associated with the Company achieving future cash flows; (e) the probability of a change in control occurring during the term of the Healthcare Royalty financing agreement; and (f) the probability of an exercise of the embedded derivative instruments. The significant unobservable inputs used in measuring the fair value of the embedded derivatives are management’s revenue projections. Significant decreases in these significant inputs would result in a higher fair value measurement of the liability. Management's revenue projections used in the December 31, 2013 valuation model significantly increased from prior periods as they included an increase in projected Zohydro ER revenues based on the October 2013 Zohydro ER NDA approval date. This significant increase in management's revenue projections led to a significant decrease in the fair value of embedded derivative liability as of December 31, 2013.