Consolidated Balance Sheet Details (Tables)

12 Months Ended

Dec. 31, 2013

Balance Sheet Related Disclosures [Abstract]

Inventory, Net

Inventory (in thousands)

	December 31,
	2013		2012
Raw materials	$	2,770	$	4,867
Work in process	6,054		6,134
Finished goods	1,112		1,885
	$	9,936	$	12,886

Property and Equipment, Net

Depreciation is calculated on a straight-line basis over the estimated useful lives of the respective assets, as follows:

Computer equipment and software	3 years
Furniture and fixtures	3-7 years
Manufacturing equipment and tooling	3-15 years
Leasehold improvements	Shorter of estimated useful life or lease term

Property and Equipment, Net (in thousands)

	December 31,
	2013			2012
Machinery, equipment and tooling	$	12,479		$	12,325
Construction in progress	6,222			5,068
Computer equipment and software	951			961
Leasehold improvements	783			783
Furniture and fixtures	628			685
Property and equipment, at cost	21,063			19,822
Less accumulated depreciation	(8,052		)	(6,261		)
	$	13,011		$	13,561

Other Assets

Other Assets (in thousands)

	December 31,
	2013		2012
Prepaid Aradigm royalty expense	$	2,571	$	3,143
Prepaid Alkermes royalty expense	2,318		—
Debt acquisition costs	969		1,217
Deposits	431		840
Restricted cash	200		200
Other assets	125		—
	$	6,614	$	5,400

Accrued Expenses

Accrued Expenses (in thousands)

	December 31,
	2013		2012
Accrued product returns	$	5,445	$	3,034
Accrued discounts and allowances	4,239		4,088
Accrued interest expense, current portion	3,033		2,526
Accrued clinical trial costs	1,238		1,012
Accrued sales and marketing costs	1,161		304
Astellas tail payment, current portion	1,131		1,820
Other accrued expenses	2,618		1,559
	$	18,865	$	14,343

Other Long-Term Liabilities

Other Long-Term Liabilities (in thousands)

	December 31,
	2013		2012
Interest expense payable, less current portion	$	5,901	$	2,607
Deferred rent	77		214
Embedded derivatives	233		992
Astellas tail payment, less current portion	—		975
Other long-term liabilities	285		290
	$	6,496	$	5,078