Consolidated Statements of Operations and Comprehensive Loss (USD $) In Thousands, except Per Share data, unless otherwise specified	3 Months Ended		9 Months Ended
	Sep. 30, 2013	Sep. 30, 2012	Sep. 30, 2013	Sep. 30, 2012
Revenue:
Net product revenue	$ 6,897	$ 8,453	$ 22,693	$ 26,368
Contract revenue	0	0	0	8,462
Service and other revenue	271	0	398	0
Total revenue	7,168	8,453	23,091	34,830
Operating expenses:
Cost of sales	5,354	4,249	14,144	13,478
Royalty expense	281	325	901	997
Research and development	2,544	3,660	9,358	16,005
Selling, general and administrative	10,011	10,857	36,491	37,574
Restructuring	0	0	876	0
Total operating expenses	18,190	19,091	61,770	68,054
Loss from operations	(11,022)	(10,638)	(38,679)	(33,224)
Other income (expense):
Interest income	1	11	12	40
Interest expense	(1,587)	(3,463)	(4,795)	(8,730)
Change in fair value of warrant liabilities	215	(3,569)	(2,780)	(3,611)
Change in fair value of embedded derivatives	1,474	(202)	912	166
Other income (expense)	67	(1,421)	90	(1,379)
Total other income (expense)	170	(8,644)	(6,561)	(13,514)
Net loss before income taxes	(10,852)	(19,282)	(45,240)	(46,738)
Provision for income taxes	0	0	0	(5)
Net loss	(10,852)	(19,282)	(45,240)	(46,743)
Net loss per share, basic and diluted (usd per share)	$ (0.10)	$ (0.21)	$ (0.44)	$ (0.63)
Weighted average shares outstanding, basic and diluted	104,682	90,370	102,136	73,790
Comprehensive loss	$ (10,852)	$ (19,282)	$ (45,240)	$ (46,743)