Consolidated Statements of Operations and Comprehensive Loss (USD $) In Thousands, except Per Share data, unless otherwise specified	3 Months Ended
	Mar. 31, 2013	Mar. 31, 2012
Revenue:
Net product revenue	$ 6,981	$ 9,885
Contract revenue	0	8,462
Total revenue	6,981	18,347
Operating expenses:
Cost of sales	4,158	5,062
Royalty expense	282	357
Research and development	3,236	5,964
Selling, general and administrative	14,482	14,649
Total operating expenses	22,158	26,032
Loss from operations	(15,177)	(7,685)
Other income (expense):
Interest income	8	19
Interest expense	(1,613)	(2,678)
Change in fair value of warrant liabilities	(4,258)	49
Change in fair value of embedded derivatives	(81)	38
Other income (expense)	66	(30)
Total other income (expense)	(5,878)	(2,602)
Net loss before income taxes	(21,055)	(10,287)
Provision for income taxes	0	(5)
Net loss	(21,055)	(10,292)
Net loss per share, basic and diluted (usd per share)	$ (0.21)	$ (0.16)
Weighted average common shares outstanding	100,809	65,369
Comprehensive loss	$ (21,055)	$ (10,292)