Consolidated Statements of Operations (Unaudited) (USD $) In Thousands, except Per Share data, unless otherwise specified	3 Months Ended		6 Months Ended
	Jun. 30, 2012	Jun. 30, 2011	Jun. 30, 2012	Jun. 30, 2011
Revenue:
Net product revenue	$ 8,030	$ 8,674	$ 17,915	$ 16,151
Contract revenue	0	1,563	8,462	3,126
Total revenue	8,030	10,237	26,377	19,277
Operating expenses:
Cost of sales	4,167	3,975	9,229	8,850
Royalty expense	315	333	672	630
Research and development	6,381	8,882	12,345	17,406
Selling, general and administrative	12,068	15,039	26,717	27,940
Total operating expenses	22,931	28,229	48,963	54,826
Loss from operations	(14,901)	(17,992)	(22,586)	(35,549)
Other income (expense):
Interest income	10	3	29	19
Interest expense	(2,589)	(1,261)	(5,267)	(2,515)
Change in fair value of warrant liability	(91)	0	(42)	0
Change in fair value of embedded derivatives	330	0	368	0
Other income (expense)	72	79	42	(103)
Total other income (expense)	(2,268)	(1,179)	(4,870)	(2,599)
Net loss before income taxes	(17,169)	(19,171)	(27,456)	(38,148)
Provision for income taxes	0	(6)	(5)	(13)
Net loss	$ (17,169)	$ (19,177)	$ (27,461)	$ (38,161)
Net loss per share, basic and diluted	$ (0.26)	$ (0.56)	$ (0.42)	$ (1.12)
Weighted average shares outstanding, basic and diluted	65,449	34,018	65,409	34,015