Consolidated Statements Of Operations (USD $) In Thousands, except Per Share data, unless otherwise specified	3 Months Ended
	Mar. 31, 2012	Mar. 31, 2011
Revenue:
Net product revenue	$ 9,885	$ 7,477
Contract revenue	8,462	1,563
Total revenue	18,347	9,040
Operating expenses:
Cost of sales	5,062	4,875
Royalty expense	357	297
Research and development	5,964	8,524
Selling, general and administrative	14,649	12,901
Total operating expenses	26,032	26,597
Loss from operations	(7,685)	(17,557)
Other income (expense):
Interest income	19	16
Interest expense	(2,678)	(1,254)
Change in fair value of warrant liability	49	0
Change in fair value of embedded derivatives	38	0
Other income (expense)	(30)	(181)
Total other income (expense)	(2,602)	(1,419)
Net loss before income taxes	(10,287)	(18,976)
Provision for income taxes	(5)	(7)
Net loss	$ (10,292)	$ (18,983)
Net loss per share, basic and diluted	$ (0.16)	$ (0.56)
Weighted average shares outstanding, basic and diluted	65,369	33,973