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Consolidated Statements Of Operations (USD $)
In Thousands, except Per Share data
3 Months Ended9 Months Ended
Sep. 30, 2011
Sep. 30, 2010
Sep. 30, 2011
Sep. 30, 2010
Revenue:    
Net product revenue$ 8,835$ 5,710$ 24,986$ 11,828
Contract revenue1,5631,3484,6882,810
Total revenue10,3987,05829,67414,638
Operating expenses:    
Cost of sales5,4822,93214,3338,233
Royalty expense343216972598
Research and development10,1348,00427,54019,394
Selling, general and administrative14,70112,54042,64237,962
Total operating expenses30,66023,69285,48766,187
Loss from operations(20,262)(16,634)(55,813)(51,549)
Other income (expense):    
Interest income21214
Interest expense(2,470)(5,426)(4,984)(6,938)
Change in fair value of warrant liability546187546(12,833)
Change in fair value of embedded derivatives13701370
Other income (expense)16(253)(86)(113)
Total other income (expense)(1,769)(5,491)(4,366)(19,880)
Net loss before income taxes(22,031)(22,125)(60,179)(71,429)
Provision for income taxes(7)0(20)0
Net loss$ (22,038)$ (22,125)$ (60,199)$ (71,429)
Net loss per share, basic and diluted$ (0.59)$ (16.00)$ (1.71)$ (53.31)
Weighted average shares outstanding, basic and diluted37,3201,38335,1271,340