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Condensed Consolidated Statements of Operations and Comprehensive Loss - USD ($)
$ in Thousands
3 Months Ended 6 Months Ended
Jun. 30, 2019
Jun. 30, 2018
Jun. 30, 2019
Jun. 30, 2018
Income Statement [Abstract]        
Revenue $ 0 $ 0 $ 0 $ 0
Operating expenses:        
Research and development 8,572 12,209 18,203 24,642
General and administrative 3,618 3,351 7,264 6,620
Total operating expenses 12,190 15,560 25,467 31,262
Loss from operations (12,190) (15,560) (25,467) (31,262)
Other income (expense):        
Interest income 561 324 1,203 591
Interest expense (478) (466) (978) (924)
Foreign currency transaction (losses) gains, net (22) (73) 1 (136)
Total other income (expense), net 61 (215) 226 (469)
Net loss $ (12,129) $ (15,775) $ (25,241) $ (31,731)
Net loss per share, basic and diluted $ (0.32) $ (0.57) $ (0.68) $ (1.15)
Weighted average common shares outstanding, basic and diluted 37,326,853 27,565,064 37,320,436 27,553,394
Comprehensive loss:        
Net loss $ (12,129) $ (15,775) $ (25,241) $ (31,731)
Other comprehensive income:        
Unrealized gain on marketable securities 29 43 63 52
Total other comprehensive income 29 43 63 52
Total comprehensive loss $ (12,100) $ (15,732) $ (25,178) $ (31,679)