Summary of Significant Accounting Policies (Details 2) - USD ($)	3 Months Ended		9 Months Ended
	Sep. 30, 2018	Sep. 30, 2017	Sep. 30, 2018	Sep. 30, 2017	Jan. 02, 2018	Dec. 31, 2017
Liabilities:
Deferred Revenue	$ 2,686,000		$ 2,686,000		$ 2,952,000	$ 12,313,600
Stockholders' Equity:
Accumulated Deficit	(90,622,193)		(90,622,193)		$ (82,338,775)	$ (91,816,655)
Collaboration Revenue	314,500	$ 74,696	1,652,520	$ 407,518
Operating Loss Before Other Expenses	(3,177,878)		(8,355,245)
Net Loss	(3,123,836)	(4,140,368)	(8,283,418)	(10,386,885)
Comprehensive Loss	(3,117,454)	$ (4,137,096)	(8,273,796)	$ (10,380,692)
Previous Accounting Guidances [Member]
Liabilities:
Deferred Revenue	13,618,600		13,618,600
Stockholders' Equity:
Accumulated Deficit	(101,517,793)		(101,517,793)
Collaboration Revenue	0		0
Operating Loss Before Other Expenses	(3,492,378)		(10,007,765)
Net Loss	(3,438,336)		(9,935,938)
Comprehensive Loss	(3,431,954)		(9,926,316)
Adopting New Revenue Guidance [Member]
Liabilities:
Deferred Revenue	(10,932,600)		(10,932,600)
Stockholders' Equity:
Accumulated Deficit	10,895,600		10,895,600
Collaboration Revenue	314,500		1,652,520
Operating Loss Before Other Expenses	314,500		1,652,520
Net Loss	314,500		1,652,520
Comprehensive Loss	$ 314,500		$ 1,652,520