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Accrued Expenses
12 Months Ended
Dec. 31, 2017
Accrued Liabilities [Abstract]  
Accounts Payable and Accrued Liabilities Disclosure [Text Block]
4. Accrued Expenses
 
Accrued expenses consist of the following:
 
 
 
December 31,
 
 
 
2017
 
2016
 
Clinical Trials
 
$
807,322
 
$
770,158
 
Payroll and Benefits
 
 
788,551
 
 
668,802
 
Professional Fees
 
 
149,273
 
 
174,342
 
Consulting
 
 
57,487
 
 
44,983
 
Short-Term Portion of Capital Lease Obligation
 
 
11,214
 
 
12,645
 
Total Accrued Expenses
 
$
1,813,847
 
$
1,670,930